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Our Endocannabinoid System (ECS) Proudly Presents the MAESTROS of the CB1, CB2, CB3? + 400 Human Orchestra!
Healthful relationships play a large role in the quality of our everyday existence. From our family bonds, the environments in which we live, the food we eat, how we physically feel, to how we see ourselves. Certain connections are critical for balance to make it all work together. This is particularly true for our body, which has a life-essential regulatory system based on biochemical relationships that helps us maintain equilibrium, despite life’s up and downs. These connections comprise the Endocannabinoid System (ECS). Hemp has a unique and interactive lock and key relationship with ECS.
The ECS “Orchestra”
What exactly is ECS? Discovered in the 1990s, ECS is thought to be one of the most vital yet vast receptor systems for sustaining good health. ECS affects many biological processes in humans, in fact, it affects all vertebrate animals, as well as some invertebrates.
ECS contains cannabinoid receptors or “locks,” while the group of chemical compounds called cannabinoids, should be viewed like “keys.” The body produces various endogenous cannabinoids, most notably anandamide and 2-arachidonoylglycerol (2-AG) and are found in the immune system, the central nervous system, brain, various organs, connective tissue, and glands.
Since hemp contains elevated levels of Cannabidiol (CBD), active phytocannabinoids work in concert with other secondary phytocannabinoids and compounds (i.e. terpenes and flavonoids), and works well with the ECS in order to unlock the receptor locks. Think of hemp as the ‘Conductor” to the receptors.
The major function of the ECS is to maintain system homeostasis by providing a state of internal stability necessary for survival, despite fluctuations in the external environment. The ECS is also involved in many physiological processes like appetite, sleep, digestion, mood, memory, metabolism, neuro-protection, hormones, and heart function.
The ECS has a series of receptors in cells throughout the body that binds the cannabinoids found in hemp extract oil. Two main kinds of receptors are cannabinoid 1 (CB1) and cannabinoid 2 (CB2) and they receive three types of cannabinoids:
Endocannabinoids – Cannabinoids made in our body
Phytocannabinoids – Derived from natural plant cannabinoids
Synthetic Cannabinoids – Synthetically created
CB1 is mostly found in the brain, as well as in the lungs, kidney, liver, bones, heart, male and female reproductive organs. This receptor is more keyed into THC (tetrahydrocannabinol), the main cannabinoid in marijuana. CB2 however lives in the immune system, with a significant presence in the spleen as well as the lungs, liver, bone and muscle. Metabolic enzymes, FAAH and MAGL, are used by the ECS to accelerate chemical reactions and efficiently break down cannabinoids once they’ve served their purpose.
Understanding the relationship with the Endocannabinoid System and homeostasis is key. It’s essential as to how we thrive, heal and function for body and mind wellness. Through science additional answers will continue to reveal why our body is responsive to hemp and whole-plant cannabinoids as much still appears to be unknown.
In other words, until we learn each instrument’s role in our body’s harmonious relationship, we will be just waiting in line for our true masterpiece to be performed. Or we can become better in tune with practicing for our personal symphony.