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CBD Research Studies The ” C ” Word

Recently my research has found this interesting documentation about canabis oil (actual Full Spectrum CBD in independent studies.)

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Just fell over this – a little research documentation regarding Cannabis and cancer…. I decided to post the complete studies myself. Undergoing my secondary verifications 😊 πŸ˜ƒ.

β€²β€² Therapeutic cannabis oil and its carcinogenic methods
There are cannabinoids that have anti-tumor properties such as THC and CBD, among others. In preclinical models, it has been possible to demonstrate antitumour activity in different types of tumours such as brain tumors (Gliomas), Skin (Melanoma and Kutan-Squamous cell carcinoma), chest, pancreas, liver and prostate tumours, among others (Munson y cols., 1975; Galve-Roperh cols., 2000; Velasco y cols., 2012; Velasco y cols., 2016).

The cannabinoids activate CB1 and CB2 receptors present in the tumour cells, thus initiating a complex route of intracellular signalling that causes cells to die (Carracedo y cols., 2006; Salazar y cols., 2009 ; Velasco y cols., 2012; Hernandez-Tiedra y cols., 2016).

In addition to causing the tumour cells β€²β€² suicide β€œ, cannabinoids also inhibit the excretion of VEGF factor needed to form the cancer’s blood vessels. This means that nutrients necessary for growth of tumour is blocked (Blazquez y cols., 2003; Blazquez y cols., 2004).

A third antitumor effect is the cannabinoids ability to modulate the effect of certain enzymes (Metalloproteases) involved in remodeling the extracellular matrix, which is an important aspect of the ability to migrate and invasion of the tumour (Blazquez y cols., 2008; Velasco y cols., 2012; Velasco y cols., 2016).

In addition to the direct effects on the tumour and its growth, cannabinoids can provide beneficial effects as an adjuvant treatment for some types of tumours (cerebral gliomas). Animal studies have shown that cannabinoids can enhance both chemotherapy (Torres y cols., 2011) and radiotherapy (Scott y cols., 2014).

In the palliative treatment (non-curative symptomatic treatment) of tumours, cannabinoids improve many symptoms that occur frequently during chemotherapy such as nausea, vomiting, loss of appetite, physical pain or insomnia β€²β€²


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