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Florida to Remove Caps on Hemp THC content.

Over the past month, hemp entrepreneurs have traveled to the Florida State Capitol to advocate against a proposal to regulate hemp-derived products that could potentially hurt the hemp industry.

But Monday, many of those same professionals were cheering after the sponsor of the latest version of the bill removed any reference to limiting the THC dosage of those hemp-derived products. THC is the compound in the cannabis plant that can get you high.

In a committee meeting Monday, Manatee County House Republican Will Robinson Jr. said: “All caps are O.U.T., Out.”

Robinson was responding to a colleague, Democrat Anna Eskamani, of Orlando, on the committee. Robinson confirmed to her that his new amendment to the legislation would remove any references to capping the amount of THC in hemp products.

That means that products in hemp stores are not going to be affected in terms of their potency to consumers.

At the same time, the bill is still moving on issues regarding safety. The measure still maintains the safety requirements to keep products like Delta-8 THC out of the hands of those under age 21, provisions that aren’t remotely controversial and have been embraced by virtually everyone who has testified in three previous committee meetings held in the House and Senate.

“We’ve sure come a long way on this one,” said Florida Cannabis Action Network president Jodi James.

“You did a great job – saved a lot of businesses,” added William Clark from the Libertarian Party of Florida.

Carlos Hermida owns a hemp dispensary in Tampa and has attended previous committee meetings about the bill. He opted not to travel to Tallahassee Monday when he saw Robinson’s amendment added to the legislation last Friday.

“The public spoke and Robinson listened!” Hermida told the Phoenix in a text message. “I can’t help but be thankful to the representative for protecting the hemp industry and protecting our children.”

As originally written, Robinson’s bill HB 1475 (as well as a similar version in the state Senate) set limits on how much THC could be included per serving and per package of hemp products. Robinson raised the limits after the bill received its first hearing in a House committee, but hemp advocates said the limits still were far too low and would have made hemp-derived products less potent for consumers to purchase and thus threaten their businesses.

Robinson admitted that “there is more work to be done in this space,” but said that it was also a great indication that the committee process works. “It’s very important to take input from stakeholders and others,” he said.

The measure was unanimously approved by the House Infrastructure Committee, its third and final committee and now will go to the House floor. Its Senate equivalent (SB 1676) is scheduled to go before the Fiscal Policy Committee on Thursday of this week.

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2023 Farm Bill to Support Production of Newly Legalized Hemp Farming

  • Hemp absorbs twice as much carbon per hectare of land than a forest does, and hemp-derived products can be used to replace paper, petroleum-based plastics, and cotton fibers.
  • In 2021, the U.S. hemp market was reported to be worth $824 million in 2021. By 2030, the global hemp market is predicted to be worth $17.24 billion.
  • The 2023 Farm Bill offers an opportunity to iron out ambiguities surrounding hemp production that will benefit farmers and stabilize the market. The upcoming Farm Bill is also an opportunity to create hemp policies that recognize the historical injustices that Indigenous and Black farmers have experienced.

Across the aisle, the question of how to handle the production of industrial hemp, a newly legalized crop, is on legislators’ minds. As the 2023 Farm Bill begins to come into focus, this carbon-sequestering plant has the potential to reshape U.S. agriculture.

Hemp absorbs twice as much carbon per hectare of land than a forest does, and hemp-derived products can be used to replace paper, petroleum-based plastics, and cotton fibers. But hemp, a strain of the Cannabis plant (from which marijuana is derived), was previously considered a Schedule I substance—the most highly regulated narcotics under the Controlled Substances Act.

The 2014 Farm Bill (P.L. 113-179legally distinguished hemp from marijuana by defining hemp as having a delta-9 tetrahydrocannabinol (THC) level below 0.3 percent, which is insufficient to produce narcotics. But it limited hemp cultivation to research purposes only. The 2018 Farm Bill (P.L. 115-334) relaxed many restrictions and established the Domestic Hemp Production Program, making it easier for farmers to grow and sell hemp. The legalization of hemp cultivation in the United States has allowed farmers to employ the crop to promote sustainable farming practices and produce sustainable alternatives to plastics and other materials.

The 2023 Farm Bill can serve as an opportunity to ensure hemp is cultivated and produced to its fullest potential. Ambiguities in federal laws must be addressed to ensure that the hemp market, which was reported to be worth $824 million in 2021, continues growing.

Power to the Plant

Much of hemp’s appeal as a sustainable solution stems from its carbon sequestration rate. In an interview with Dezeen, Cambridge University researcher Darshil Shah stated that hemp can capture between 10 and 15 tons of atmospheric carbon dioxide (CO2) for each hectare of cultivation, a rate twice that of forests. Its fast growth rate means that farmers have the opportunity to harvest hemp multiple times per year, priming it for climate mitigation efforts.

 

 

Cultivating hemp doesn’t require the heavy use of pesticides or large amounts of water, and with such water-input versatility, the plant can be grown in a variety of types of soils and climates. When planted, hemp can be used as a cover crop and bolster the soil nutrient profile. The plant can also help stabilize erosion with its deep roots that also absorb and remove heavy metals from the ground.

Hemp’s high yields hold the promise of replacing other fiber- and oil-producing plants. According to the National Hemp Association, one acre of hemp produces double the amount of oil than an acre of peanuts does, and it also produces four times as much fiber pulp used for paper than an acre of trees does. When processed, every part of the hemp plant can be used for a wide range of products, including biofuels and textiles.

The wide range of versatile hemp-derived products has the potential to address U.S. reliance on plastics, fossil fuels, and cotton, by serving as a sustainable replacement. Currently, the Center for International Environmental Law predicts that plastic consumption will continue increasing and account for 20 percent of oil consumption by 2050. Hemp, however, offers a naturally biodegradable alternative that can replace petroleum-based plastic materials on both the commercial and industrial scale. Alongside bioplastics, hemp has gained prominence being a durable alternative to cotton, as it requires less land and around half of the water cotton crops need. Beyond clothing and plastics, hemp has been used in construction with products like hempcrete, and its seeds have been used in cosmetics and in food for their nutritional value. With this plethora of sustainable benefits, hemp has the potential to reshape more than just agriculture.

Moreover, the carbon sequestration of hemp has the potential to reduce greenhouse gas (GHG) emissions from U.S. agriculture—which the EPA estimated accounted for 11.2 percent of total U.S. GHG emissions in 2020. By offering sustainable alternatives to high-emission products, hemp cultivation could help the United States meet its climate goals.

Addressing Diversity in Farming via Hemp

Though the legislative focus on industrial hemp has been relatively recent, Indigenous peoples have been farming hemp long before it was legalized in the 2014 Farm Bill. Yet, current hemp legislation and its enforcement do not quite recognize this—nor do they treat Indigenous farmers equally to their white counterparts.

In 2015, the Drug Enforcement Administration (DEA) seized 30,000 hemp plants and invaded sovereign land belonging to the Menominee Indian Tribe of Wisconsin, claiming that these plants violated the law as they were intended to produce marijuana. The Menominee Indian Tribe of Wisconsin filed a lawsuit against the DEA agents for the destruction of their crops. They claimed that they were legally growing hemp on their lands for research by the College of the Menominee Tribe, yet the judge agreed with the DEA’s attorney and dismissed the lawsuit.

This case is an example of how the enforcement of hemp legislation is complicated by the history of Indigenous land dispossession by the U.S. government. Environmental activist and member of the Ojibwe tribe Winona LaDuke is advocating for both the environmental benefits and social benefits of hemp policy crafted with respect to communities of color, their histories, and their beliefs.

Writing for the Esperanza Project, LaDuke spotlights how plots of hemp qualify as carbon sinks, with the plant itself being capable of replacing carbon-intensive materials. LaDuke notes that these qualities offset GHG emissions, which prompts ecological restoration that can be led by young Indigenous leaders. Thus, there is potential for hemp production to provide added income to Indigenous communities and act as part of a path toward a sustainable, circular economy.

The hemp market is predicted to continue to grow and reach a global value of $17.24 billion by 2030. With this growth comes the opportunity for more farmers to get involved—farmers such as Indigenous and Black farmers who have been traditionally left behind by agricultural policies. Hemp can be grown on small plots of land, a trait beneficial for farmers of color who typically do not own the same large expanses of land that their white counterparts do.

Black and Indigenous communities in the United States have faced a history of exclusion from land ownership and economic opportunities, and this history has shaped their access to agriculture today. According to a 2012 USDA report, only 1.4 percent of the country’s 3.2 million farmers are Black farmers as a result of discrimination from lending institutions, including the USDA. Black farmers are hoping to see hemp policy address historical injustices in agriculture.

A change to hemp licensing would be a first step to addressing historical injustices. Federal law requires farmers applying for hemp licenses to not have had a drug felony in the past 10 years. As the Drug Policy Alliance reports, Black and Latinx people are more likely to have marijuana-related drug felonies which, under this policy, further excludes them from harvesting the benefits of hemp.

A lack of hemp education is another issue affecting both Black and Indigenous farmers that hemp policy could address. The Pew Charitable Trusts has reported on organizations forming to educate people on hemp, what it is, and how to acquire a license for it. Such education could be undertaken by the federal government to ensure that hemp production is inclusive and sustainable for all.

Hemp’s Future in the Farm Bill

The Farm Bill has always been an opportunity for policymakers to address agricultural and food issues on a federal level. The federal government defined industrial hemp, differentiating it from marijuana, and developed the Hemp Research Pilot program to legalize hemp cultivation for research purposes in the 2014 Farm Bill. Outside of research, hemp production was still illegal under federal law. The 2018 Farm Bill legalized hemp cultivation outside of pilot products, though it also restricted the THC content of hemp plants.

hemp_graphic.png

Moreover, the 2018 Farm Bill legalized hemp production in states, territories, and tribal lands, and hemp was added to the Federal Crop Insurance Act to ensure that hemp farmers receive government assistance for crop losses. It also took what has been considered a first step in addressing inequity in farming: states must report to Congress how much funding they’re providing to their historically Black land-grant colleges and universities and also to predominantly white institutions.

Ahead of the 2023 Farm Bill, the House Agriculture Subcommittee on Biotechnology, Horticulture, and Research held a congressional hearing to see how the next Farm Bill could improve hemp production. In this hearing, the need for clear regulations around CBD (the active ingredient in cannabis derived from hemp plants) and for stronger supply chain processing were highlighted, alongside further opportunities for hemp-derived products within climate markets.

Frustration and confusion around CBD laws has been a topic of concern for hemp farmers since the 2018 Farm Bill. Now, it is one of the issues hemp industry advocates hope to see addressed in the 2023 Farm Bill. Beyond CBD, the National Hemp Association is hoping to see three other major changes. It is advocating for a specific carve-out for hemp grain and fiber to develop a framework for promoting these products, for hemp grain to be allowed as animal feed to support farmers, and for the THC limit to be raised to one percent instead of 0.3 percent. Raising the THC limit has been discussed by numerous hemp organizations and farmers, as a one percent limit provides leeway and lessens the need for crops to be destroyed.

The National Law Review highlights further hemp-related changes that may be included in the 2023 Farm Bill, one of which being the revision of the broad definition of hemp. Currently, only delta-9 THC has been regulated in the 2018 Farm Bill, and there are worries that this is a loophole for unregulated hemp sales of other kinds of THC. Moreover, federal laws do not address what happens when the THC level of raw hemp exceeds the 0.3 percent allowed, even if it is ultimately processed into a product that will have a lower THC percentage (this is often referred to as “in-progress” hemp).

With many organizations highlighting the need to iron out ambiguities surrounding hemp laws, the 2023 Farm Bill may be the prime opportunity to do so. Including smart hemp production and cultivation policies in the 2023 Farm Bill has the potential to make the hemp industry more sustainable, inclusive, and profitable.

Author: Lynlee Derrick

We, at Inspirational Technologies are at the forefront of Inspirational and Frontrunners on the frontier of current technology. We are often faced with our own personal conflicts which directly influence our interactions with our peers and family. 

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Why Some Enjoy Smoking Weed While Others Feel Anxious?

Did you ever wonder why cannabis doesn’t affect everyone the same way? Why do some people experience pleasure and relaxation when smoking pot and others get anxious or even paranoid?

Psychiatrist: Why Some Enjoy Smoking Weed While Others Feel Anxious? Does Frequent Use Change Personality?

Psychiatrist: Why Some Enjoy Smoking Weed While Others Feel Anxious? Does Frequent Use Change Personality?© Provided by Benzinga

To understand the various effects the same plant has on the same species, we humans that is, it’s essential to understand not only the plant and its components, but our own endocannabinoid system.

Enter neuroscience.

First things first, what is the endocannabinoid system?

Simply put, it is a biological system in the body that helps regulate and balance key bodily functions. An American psychiatrist with a private practice in San Francisco and Marin County focuses on addictions. In his book, “Marijuana on My Mind: The Science and Mystique of Cannabis,” Timmen L. Cermak, M.D. explores various questions about marijuana and its effects.

In his January post in Psychology Today, Cermak tries to explain how it feels to be high and why this experience can sometimes resemble meditation. In a new post, he focuses on “how THC and CBD ingestion produces pleasant effects for so many people, why too frequent use of cannabis can produce subtle cognitive and emotional impairments, and how selective use of cannabis has medicinal benefits for a variety of illnesses.”

Cermak looks at Koen Van Laere’s discovery of how genetic differences in the density of active CB1 receptors determine temperamental characteristics of extroversion exhibited in novelty-seeking and often risk-taking and introversion’s novelty and risk avoidance.

Cermak explains how THC increases endocannabinoid system activity, lowering the bar for experiencing novelty. This is why, when some people are, they notice things that they hadn’t noticed a long time ago, like the rainbow on each soap bubble. For some cannabis consumers, weed can help them become more fascinated with the everyday world.

On the other hand, too frequent cannabis use leads to raising the bar for experiencing novelty higher than normal, thus leading to a sense of boredom. “High cannabinoid activity produces novelty; low cannabinoid activity reduces novelty,” writes Cermak.

This means that people born with low CB1 receptors may feel good when THC increases their amygdala endocannabinoid system activity, as it “brightens their interest in the world.” On the other hand, people with high CB1 receptors who are already close to saturation with novelty could be overwhelmed with THC to the point of feeling anxious.

Temperament & Personality

Cermak notes an important distinction between temperament and personality when he says that “temperament is genetically determined and should not be conflated with personality.” He explains that two people with the same temperamental trait of novelty-seeking can develop two destructive personalities: “one becoming an inveterate world traveler while the other becomes ensnared in a series of drug addictions.”

In the end, Cermak highlights how Laere’s research offers a basis for understanding why the 20% reduction in CB1 receptors caused by frequent marijuana use could lead to temperament and ultimately personality changes. However, research confirming this theory would be unethical, so all we can do is trust anecdotes that indicate how regular marijuana use is related to various personality changes.

 

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Members of the Texas House of Representatives advanced legislation seeking to expand cannabis products.

Members of the Texas House of Representatives advanced legislation today seeking to expand the pool of patients eligible to obtain state-licensed cannabis products.

Lawmakers voted by a nearly five to one margin in favor of the legislation, House Bill 1805. Specifically, it amends the Texas Compassionate Use Program so that physicians may recommend certain products containing fixed levels of THC to patients with “a condition that causes chronic pain, for which a physician would otherwise prescribe an opioid.” It also empowers state health officials, rather than lawmakers, to add additional qualifying conditions. Currently, patients with autism, ALS, cancer, incurable neurological disorders, intractable epilepsy, multiple sclerosis, post-traumatic stress, and seizure disorders are eligible to obtain low-THC medical cannabis products.

The measure also amends limits on the amount of THC that may be present in state-licensed products.

“I am thrilled to see the proposed legislation advancing through the legislative process,” said NORML State Policies Manager Jax James, who also serves as Executive Director for Texas NORML. “Medical cannabis is an objectively safer alternative to the array of pharmaceutical drugs that it could potentially replace. I urge my fellow Texans to voice their support for this important legislation and to reach out to their Senators to encourage their backing as it moves through the legislative process.”

Texas NORML 2013 Recap - Texas NORML

Texas lawmakers initially enacted legislation establishing the Compassionate Use Program in 2015. In 2021, legislators expanded the program to allow patients with PTSD and all forms of cancer to qualify for medical cannabis. That legislation also raised the limit on permissible levels of THC in licensed products from 0.5 percent to one percent.

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CBDH Research Shows Painkilling Properties. What is CBDH?

Reported on the much-discussed scientific discovery of a THC analog thirty times more efficacious than the infamous D9-THC. An earlier study found THCP, as well as CBDP, which are larger forms of THC and CBD, respectively. Now, the same team of researchers from Italy bridged a gap between regular CBD and CBDP. They found a unique form of THC as well as CBDH, a new cannabinoid for pain. 

The size of the cannabinoid depends, mostly, on the number of carbon atoms. Regular THC and CBD have side chains that consist of five carbon atoms, and the ‘phorol‘ cannabinoids contain seven. Whereas, CBDH (cannabidihexol) is a hexyl cannabinoid with a six-carbon sidechain. (1)

NEW THC FOUND WITHOUT LUCK

Adding to the discovery, the team also found THCH (Δ9– tetrahydrocannabihexol). However, the quantity they collected was insufficient for further tests. It is still unknown if THCH is an intoxicant; potent like THC or even THCP. In any case, the new variants came as no surprise considering a cannabinoid that resembles THCH was synthesized in 1949. This artificial substance, known as parahexyl, is psychoactive and similar in structure to THCH. So, the researchers decided to check. They had to make sure they were looking at new natural analogs of THC and CBD, not some previously known methylated groups.

The Regional European Development Fund financed the research project in Florence, Italy. The team studied a strain known as CIN-RO, which was bred by the Council for Agricultural Research and Economics (CREA) in Rovigo, Italy. And like all cannabis approved for research in the boot-shaped nation, the Italian Military cultivated and provided the cannabis. 

Institute of Research Italy
Stabilimento Chimico Farmaceutico Militare

CBDH OR BUST 

When the team isolated CBDH, on the other hand, they collected enough to study its effects on mice. Interest that the researchers took in CBDH in this study contrasted the team’s research on phorol cannabinoids (THCP) one year prior. The earlier scientific discovery disregarded CBDP for its lack of cannabinoid receptor activity. But, regular CBD, with a five-carbon chain, lacks true activity at the cannabinoid receptor and instead has an allosteric relationship that took decades for man to truly appreciate. Now, the market is flooded and stocks have gone to mushrooms. 

ORIGINS OF AN ANALGESIC CANNABINOID

Thankfully, without enough THCH on hand, the researchers took interest in CBDH and the new cannabinoid’s effect on pain. CBDH produced strong antinociceptive (painkilling) properties in mice at an (intraperitoneal) dose of one and two milligrams per kilogram. Interestingly, that effect was void at a higher dose of five milligrams per kilogram. The low dose is on par with regular CBD, but CBDH has atypical effects at larger doses which suggests a biphasic effect. 

The team hypothesized the presence of CBGH as a logical origin of other hexyl-cannabinoids. This is because CBG is the origin of both, THC and CBD, much like CBGV which becomes CDBV or THCV. After much analysis, however, they did not find CBGH or any related cannabinoid. In the end, they could not determine how the hexyl cannabinoids, THCH and CBDH, formed in the plant. Clearly, science requires more research to truly understand new variants of THC and CBD found in analytical success stories.

CBDH exhibits pain-relieving qualities (much like its CBD counterpart)

This is the most interesting part of the study. When the Italian researchers identified CBDP a year ago, they found it had very little affinity with cannabinoid receptors and didn’t activate them the same way THCP did.

The same cannot be said for CBDH — not even in the slightest. 

Researchers were able to obtain a sufficient sample of CBDH and analyze its pharmacological effects in mice test subjects. They found lower doses were more effective for pain relief and pain management. 1.2 mg/kg of CBDH reduced pain response and 2 mg/kg of CBDH significantly blocked the physiological detection of pain.

CBDH and THCH molecular structure

Interestingly, higher doses (3 and 5 mg/kg) had no pain-relieving effects, which isn’t wholly uncommon. High doses of certain cannabinoids don’t necessarily equate to more effective. Low and medium doses of, say, THC can be more effective than higher doses for certain ailments. 

What the researchers say about CBDH’s pain-relieving properties

The researchers believe CBDH’s pain-relief and pain-management qualities could be the result of vanilloid receptor activation (TRPV1), which helps mediate pain, pain-perception, and body temperature. In higher doses, however, they believe CBDH may block CB1 and CB2 receptors involved in the body’s response to pain, causing no pain-relief at all. 

How does this differ from CBD?

CBD isn’t known for having the greatest relationship with your endocannabinoid system. Doesn’t bind to either cannabinoid 1 or cannabinoid 2 receptors. In fact, it barely even touches them (not directly at least). CBD has more of an affinity with other receptor sites e.g. serotonin (5-HT) receptors and the aforementioned vanilloid (TRPV1) receptors. 

CBD’s targeting of serotonin and vanilloid receptors produces different effects and benefits from each other. Serotonin activation produces anti-depressant and anti-anxiety effects in rodent test subjects, whereas vanilloid activation results in the mediation of pain-perception, inflammation, and body temperature.

Because CBDH’s molecular structure is almost similar to CBD’s (CBDH has a six-alkyl side chain, while CBD has a five-alkyl side chain), it’s not unreasonable to assume they act in a similar way. 

Everything You Need To Know About CBD!

How CBDH could be used 

To be perfectly honest, we can only surmise CBDH’s real-world uses based on one study.

If CBDH is a powerful pain-reliever in mice test subjects, there’s scope to suggest low-to-moderate isolated doses, alongside other analgesic cannabinoids such as CBD, CBG, and THC could be used in clinical treatment in the future. 

This isn’t for certain, though. So much more needs to be looked at before we can accurately evaluate its uses beyond limited preclinical animal studies. We look forward to seeing how this exciting cannabinoid develops in the future. 

Key Points:

  • In low doses (1.2–2 mg/kg), CBDH reduced pain in mice test subjects. In higher doses (2–5 mg/kg), there was no pain-relieving effect. 
  • Image result for CBDH reduced pain
  • CBDH’s pain-relief qualities might be the results of vanilloid receptor activation — vanilloid receptors mediate pain and pain management.
  • Real-world use of CBDH is still unknown but could be used as a potent pain-relief cannabinoid.

Researchers were unable to sufficiently test THCH’s effects

It’s always super exciting to read about a new THC variant. THC itself is a phenomenal cannabinoid responsible for a whole heap of amazing benefits such as pain relief, neuroprotection, sleep problems, antibacterial, and antiinflammation. Its variants (delta-8-THCTHCV, etc) are also incredibly useful to you.

Unfortunately, researchers were unable to extract enough THCH to sufficiently evaluate how it interacts with rodents. It’s unknown whether THCH is intoxicating or has unique benefits similar (or separate) from THC and its other variants. 

However, a near-identical synthetic homolog of THC was inadvertently created in 1949 after scientists attempted to understand THC’s effects. This homolog, known as parahexyl (n-hexyl-Δ3-THC), is intoxicating, presumably binding tightly to CB1 receptors. Used as an anti-anxiety treatment in the 20th century but later banned and placed as a Schedule I controlled substance. 

Does THCH cause these effects and benefits? Maybe. But we’ll only know when more research is carried out.


There are currently no CBDH or THCH-centered products on the market

Over the past couple of years, cannabis brands and manufacturers have sight their sights on other cannabinoids away from CBD and THC. High percentages of isolated minor cannabinoids such as CBG, CBN, and CBC can now be found in several products across the US.

Right now, CBDH and THCH are naturally found in regular cannabis products but not in high percentages. 

Image result for CBDH reduced pain

It might be a while before we see CBDH or THCH isolated into a product but we’re more than excited to see it!

Or will CBDH become tomorrow’s wash of marketing gimmicks

SOURCES

  1. Linciano, P., Citti, C., Russo, F. et al. Identification of a new cannabidiol n-hexyl homolog in a medicinal cannabis variety with an antinociceptive activity in mice: cannabidihexol. Sci Rep10, 22019 (2020). doi/10.1038/s41598-020-79042-2
  2. Morano, A., Fanella, M., Albini, M., Cifelli, P., Palma, E., Giallonardo, A. T., & Di Bonaventura, C. (2020). Cannabinoids in the Treatment of Epilepsy: Current Status and Future Prospects. Neuropsychiatric disease and treatment16, 381–396. https://doi.org/10.2147/NDT.S203782

We, at Inspirational Technologies are at the forefront of Inspirational and Frontrunners on the frontier of current technology. We are often faced with our own personal conflicts which directly influence our interactions with our peers and family. 

When Inspirational Technologies is an endorsement of the “Cannabis” approach to the medical condition, we say, let’s let the look at the data and the people who say that they benefit for cannabis alternatives.

 

 

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What is CO2 Extraction? What Hemp and Marijuana Growers Need to Know.

 

 

What is CO2 Extraction? The Supercritical CO2 extraction process creates phase changes in carbon dioxide utilizing temperature and pressure.

CO2 is known as a “tunable solvent” making it extremely versatile for creating a multitude of end products by controlling temperature and pressure.

These phase changes create an environment to drop out differing weights of components in the plant material.

The unique design of the Hi-Flo™ Series systems allow for separation and collection of these constituents during a single extraction.

This enables collection of light essential oils separately from other desirable constituents and heavier lipids.

Supercritical CO2 fluid extraction (SCFE) methodology delivers a clean, unaltered, consistent-yet-flexible product.

Removable Molecular Components is a Positive Clean Alternative for CBD Extraction

CO2: Clean, Safe, Quick CO2 Extraction is good business.

It allows you to create a pure, clean, quality oil that is safe to produce with little-to-no post-processing.

Processes that use toxic solvents may require many hours to purge the solvent trapped in the oil.

Multiple industries have proven that the highest efficiencies in commercial processing utilize CO2. CO2 offers you the ability to “tune” the extraction process, especially with a system that will separate constituents during an extraction.

You can target specific compounds, like terpenes (terpenoids) and THC/CBD (cannabinoids) through different operational parameters.

CO2 is also a sanitizing agent, prolonging shelf life, and, with t

he proper system and environment, yields food and medical grade oils.

CO2 extraction is a safe, clean, and highly versatile method of extracting plant botanicals, nutraceuticals, hops, and hemp.

For the Originality in Extraction

Supercritical carbon dioxide (sCO2) is the most widely used fluid for the Supercritical Fluid Extraction (SCFE) process across the globe. Not only is sCO2 capable of extracting the required ingredients in their pristine form, the prime reason for the surging popularity of SCFE, it also makes the process more manageable, economical, and safe.

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Buffalo Extraction Systems Carbon dioxide (CO2) Supercritical Fluid Extraction (SCFE) Plant

These days, “clean label” products are selling like hot cakes. Increasingly health-conscious customers are placing a premium on natural ingredients in the food, pharmaceutical, beverage, and neutraceutical products they consume. Now, clean label is a broad term with various meanings – organic, natural, locally grown, non-GMO . . . the list goes on. Some even take it to link its maker to more transparent work practices.

Alternative processes such as Solvent Extraction and Hydro distillation leave behind harmful residues. Plus, they distort the ingredient being extracted. That is, the ingredient does not retain its natural purity. Regulations have caught up with public demand and impose exacting conditions to ensure the quality and safety of products by limiting toxic residues. One more reason to rely on CO2 SCFE.

What Makes Supercritical Carbon dioxide (sCO2) an Exceptional SCFE Solvent?

Carbon dioxide and water are the most widely employed supercritical fluids. sCO2 makes such a useful supercritical fluid because:

  • Has a critical temperature of 31.10C, which is around the ambient temperature improving its compatibility with temperature-sensitive compounds.
  • Has a more manageable critical pressure of 73.9 bar.
  • Is non-flammable and non-toxic.
  • Has a customizable density to upgrade its solvent power.
  • Is available in ample quantities and in pure form; and
  • Has a comparatively low cost.

Although CO2 is a greenhouse gas (GHG), the SCFE process using CO2 becomes eco-friendly if the gas is captured from the atmosphere and recycled.

Carbon dioxide Supercritical Fluid Extraction (CO2 SCFE)

Solvent Extraction employs organic solvents to dissolve the ingredient from the raw material. Later, it separates the organic solvent from the dissolved ingredient. The problem is, organic solvents do not completely disassociate from the ingredient, leaving behind residues.

Parameter Solvent Extraction SCF Extraction
Solvent traces in final product Yes Zero
Heavy metal content in final product Yes Zero
Inorganic salt content in final product Yes Zero
Similarity with the actual components to be extracted in terms of Colour and Flow Characteristics Less: because polar compounds get dissolved. More: because low operating temperatures and selective extraction of CO2.

Table 1. SCFE Vs Solvent Extraction

That is, the ingredient loses its natural purity. What is more, it may develop a certain degree of toxicity. But the concerns on using organic solvents for extraction go beyond toxicity for the individual. Some solvents are ozone depleting substances, and their use negatively impacts the environment.

Hydro distillation i.e., the use of water and steam distillation inherently employs heat, something that thermally degrades the ingredients. Again, the ingredient, when extracted, is no longer available in its pure form.

Parameter Steam Distillation SCF Extraction
Extraction of essential, non-volatile oils Not possible Possible
Extraction of highly volatile oils Not possible Possible
Oxidation and Hydrolysis (undesirable) Possible Not possible
Similarity of essential oils with the extracted component in terms of Form, Aroma, and Physical Characteristics Less More

Table 2. SCFE Vs Steam Distillation

As a process that holds the United States FDA’s “Green Technology” approval, CO2 SCFE enjoys sizable international clout. One reason for its eco-friendly nature is that it does not generate effluents, automatically eliminating pollution control hassles and costs.

Examined in the context of the limitations of hydrodistillation and solvent extraction, CO2 SCFE delivers a much better performance on all fronts during the extraction of:

 

  • Plant-based Ingredients: Solvent extraction oxidizes the ingredient that lends color and aroma. Similarly, steam distillation acts strongly and ends up altering the component’s aroma. SCFE acts mildly, thereby avoiding such unwanted changes while also delivering cleaner, fresher, and crispier extracts.
  • Herbal Medicines: CO2 SCFE is preferred over hydrodistillation when extracting essential oils because it does not thermally degenerate the oil. It is also replacing solvent extraction for seed oil separation as the solvent cannot be completely disassociated from the seed oil.
  • Astaxanthin Extraction from Haematococcus pluviales: CO2 SCFE gives superior results vis-à-vis solvent extraction that employs acetone and hexane. These solvents cannot tell between astaxanthin and the astaxanthin-lipid mixture, both of which occur inside Haematococcus pluviales. As a result, these solvents deliver a low-concentrate extract.
  • Beer, Wine, and Blended Alcohol: CO2 SCFE lowers the alcohol content of wine to a bare minimum while leaving its organopletic features undisturbed. The process also extracts the original versions of hop flavors while extending their life, thereby acting as a natural preservative for beer.

Organopletic properties of wines are their aroma, fruitiness, crispiness, sweetness, and freshness. Hop is the plant whose flower imparts the prized bitter taste to beer.

  • Phytochemicals: Because supercritical CO2 is naturally nonpolar, it can better distinguish between volatile, non-polar, and low molecular weight phytochemicals [14].

The selectivity of SCFE is an asset here as it can separate anthocyanin from the pulp of Euterpe oleracea at a certain pressure while extracting phenolic phytochemicals from that very pulp at another pressure.

  • Algae:
  • Carotenoids: Hiking the pressure and temperature of the CO2 SCFE process boosts the efficiency of carotenoid extraction. Utilizing the solvent extraction process for the same consumes large quantities of solvent, takes longer, and delivers impure and deficient yields.
  • Antioxidants: Employing CO2 SCFE on Haematococcus pluvialis, a microalgae, gives good yields of lutein, astaxanthin, and fatty acids.
  • Fatty Acids: CO2 SCFE is able to better differentiate between different fatty acids as compared to pyrolysis / thermal liquefaction and solvent extraction via hexane, the traditional methods for fatty acid extraction. Besides, these conventional techniques are slower.
  • Sterols: CO2 SCFE enables solvent-free extraction of phytosterols that are safe for use in the food and beverages industries.

The Verdict

People the world over are shifting to natural alternatives – natural medicine, natural food, natural beverages – in realization to the long-term side effects that synthetic products, possibly laced with toxic residues, can unleash on health and overall wellbeing.

Effectively this means, the SCFE process and, more specifically, the CO2 SCFE process, are here to stay . . . for ages.

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*This site receives virtually no compensation for sales of some or all mentioned products. We however place humanitarian value over monetary interests. Our monetary income goes back into research, development, discovery and healing.
Inspirational Technologies – is Committed to Your Health Wellness Beauty and Enrichment
Reporting on Today’s Internal Botanical and Skin Product Benefits

4 Hemp Club was Inspired by Steven Smith’s vision to

“Have an older generation 4H Club, where an older community of adults could carry on what the younger 4H Club envisioned.

Our 4H Platform Uses HEMP as an Agricultural Focal Point, deserving of research, development and with the

4 Hemp key points being Health Hope and Happiness, thru Hemp“.

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