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Research on CBD for Fibromyalgia

Research on CBD for fibromyalgia

Fibromyalgia is a chronic pain disorder that causes musculoskeletal pain in addition to:

It mostly affects women, and currently there’s no known cure for the condition. However, treatment options are available that focus on pain management.

CBD has been used to ease chronic pain symptoms and reduce inflammation. It’s presented as an alternative to taking opioid prescriptions which can be addictive.

However, the Food and Drug Administration (FDA) hasn’t approved CBD as a treatment option for fibromyalgia or most other conditions. The CBD-based prescription drug Epidiolex, an epilepsy treatment, is the only CBD product that’s FDA-approved and regulated.Happy St. Patty’s Day – Go Green! Better clothing, better food, better gadgets. Is there anything Hemp can’t do?

There are currently no published studies on fibromyalgia that look at the effects of CBD on its own. However, some research does look at the effects of cannabis, which may contain multiple cannabinoids, on fibromyalgia.

The results have been mixed. More human studies are needed.

Earlier studies

2009 reviewTrusted Source found that CBD can be used to relieve neuropathic pain. The researchers concluded that cannabinoids such as CBD might be a useful adjunct to other pain medications.

2011 study looked at 56 people with fibromyalgia. Most of the participants were women.

Members of the study comprised two groups:

  • One group was comprised of 28 study participants who weren’t cannabis users.
  • The second group was comprised of 28 study participants who were cannabis users. The frequency of their cannabis use, or the amount of cannabis they used, varied.

Two hours after using cannabis, the cannabis users experienced benefits such as:

  • reduced pain and stiffness
  • an increase in sleepiness

They also had slightly higher mental health scores than the non-users.

2019 Dutch study

2019 Dutch study looked at the effect of cannabis on 20 women with fibromyalgia. Over the course of the study, each participant received four types of cannabis:

  • an unspecified amount of a placebo variety, which contained no CBD or THC
  • 200 milligrams (mg) of a variety with high amounts of both CBD and THC (Bediol)
  • 200 mg of a variety with high amounts of CBD and low amounts of THC (Bedrolite)
  • 100 mg of a variety with low amounts of CBD and high amounts of THC (Bedrocan)

The researchers found that the spontaneous pain scores of people using the placebo variety were similar to the spontaneous pain scores of people using some of the non-placebo varieties.

However, Bediol, which is high in CBD and THC, brought relief to a greater number of people than the placebo did. It caused a 30 percent reduction of spontaneous pain in 18 of the 20 participants. The placebo caused a 30 percent reduction of spontaneous pain in 11 participants.

Use of Bediol or Bedrocan, both high-THC varieties, significantly improved pressure pain thresholds when compared to the placebo.

Bedrolite, which is high in CBD and low in THC, didn’t show any evidence of being able to relieve spontaneous or evoked pain.

2019 Israeli study

In a 2019 Israeli study, hundreds of people with fibromyalgia were observed over a period of at least 6 months. Of the participants, 82 percent were women.

The study participants received guidance from nurses before taking medical cannabis. The nurses provided advice on:

All the participants started with a low dosage of cannabis, and dosages were increased gradually over the course of the study. The median approved dosage of cannabis started at 670 mg a day.

At 6 months, the median approved dosage of cannabis was 1,000 mg a day. The median approved dosage of THC was 140 mg, and the median approved dosage of CBD was 39 mg a day.

The researchers admitted that the study had limitations. For instance, they were only able to follow up with about 70 percent of participants. The use of so many different strains also made it difficult to compare the effects of CBD-rich and THC-rich strains.

However, they still concluded that medical cannabis was a safe and effective treatment for fibromyalgia.

At the beginning of the study, 52.5 percent of participants, or 193 people, described their pain level as high. At the 6-month follow-up, only 7.9 percent of those who responded, or 19 people, reported high levels of pain.

CBD treatment options

If you want to avoid the psychoactive effects of marijuana, you can find CBD products that contain only trace amounts of THC. If you live in a place where recreational or medical marijuana is legal, you can find CBD products that contain higher concentrations of THC.

Although they each have benefits separately, CBD and TCH likely work best when combined. Experts refer to this synergy, or interaction, as the “entourage effect.”

CBD also acts against THC-targeted receptors to reduce the negative effects of marijuana, such as paranoia and anxiety.

You can consume CBD in a number of ways, including:

  • Smoking or vaping. If you want to relieve immediate pain, smoking CBD-rich cannabis is the quickest way to reduce symptoms. Effects can last up to 3 hours. Smoking or vaping allows you to directly inhale CBD from the cannabis plant, absorbing the chemical into your bloodstream and lungs.
  • Edibles. Edibles are foods cooked with the cannabis plant, or cannabis-infused oil or butter. It’ll take longer to experience symptom relief, but the effects of edibles can last for up to 6 hours.
  • Oil extracts. Oils can be applied topically, taken orally, or dissolved under the tongue and absorbed in mouth tissues.
  • Topicals. CBD oils can be infused into topical creams or balms and applied directly to the skin. These CBD products can be an effective option for reducing inflammation and helping with external pain.

There may be respiratory risks to smoking or vaping marijuana. People with asthma or lung conditions shouldn’t use this method.

You should also follow dosage instructions carefully, especially with edibles, to avoid the negative side effects of taking too much.

STAYING HEALTHY

Cannabidiol (CBD)-what we know and what we don’t

September 24, 2021

Cannabidiol (CBD) is often covered in the media, and you may see it touted as an add-in booster to your post-workout smoothie or morning coffee. You can even buy a CBD-infused sports bra. But what exactly is CBD? And why is it so popular?

How is cannabidiol different from marijuana, cannabis and hemp?

CBD, or cannabidiol, is the second most prevalent active ingredient in cannabis (marijuana). While CBD is an essential component of medical marijuana, it is derived directly from the hemp plant, a cousin of marijuana, or manufactured in a laboratory. One of hundreds of components in marijuana, CBD does not cause a “high” by itself. According to a report from the World Health Organization, “In humans, CBD exhibits no effects indicative of any abuse or dependence potential…. To date, there is no evidence of public health related problems associated with the use of pure CBD.”

Is cannabidiol legal?

CBD is readily obtainable in most parts of the United States, though its exact legal status has been in flux. All 50 states have laws legalizing CBD with varying degrees of restriction. In December 2015, the FDA eased the regulatory requirements to allow researchers to conduct CBD trials. In 2018, the Farm Bill made hemp legal in the United States, making it virtually impossible to keep CBD illegal – that would be like making oranges legal, but keeping orange juice illegal.

Protect yourself from the damage of chronic inflammation.

Science has proven that chronic, low-grade inflammation can turn into a silent killer that contributes to cardiovas­cular disease, cancer, type 2 diabetes and other conditions. Get simple tips to fight inflammation and stay healthy — from Harvard Medical School experts.

Thank you for consideration.

What is fibromyalgia?

Fibromyalgia is a long-term, or chronic, condition. It causes symptoms such as:

  • musculoskeletal pain, or pain in the muscles and bones
  • tenderness
  • general fatigue
  • sleep and cognitive disturbances

This condition can be hard to understand, even for healthcare professionals. Its symptoms mimic those of other conditions, and there are no tests to definitively confirm a diagnosis. As a result, fibromyalgia is often misdiagnosed.

In the past, some healthcare professionals even questioned whether fibromyalgia was real. Today, it’s much better understood.

Around 4 million adults in the United StatesTrusted Source, or around 2 percent, have been diagnosed with fibromyalgia. Most fibromyalgia cases are diagnosed in females. Most people get diagnosed in middle age, but fibromyalgia can also affect children.

Some of the stigmas that previously surrounded fibromyalgia have eased, but it can still be challenging to treat. Medications, therapy, and lifestyle changes can help you manage your symptoms and improve your quality of life.

You may also experience remission-type periods in which your pain and fatigue improve.

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Marijuana Company of America, Inc. to Present at LD Micro Invitational XII Conference

Marijuana Company of America, Inc. to Present at LD Micro Invitational XII Conference on June 8, 2022


LOS ANGELES, CA June 1, 2022, Marijuana Company of America, Inc

MCOA, operates, invests, and acquires companies exclusively in the cannabis sector, today announced it will be presenting at the 12th annual Invitational hosted by LD Micro at the Four Seasons Westlake Village, on Wednesday, June 8th at 5:00 pm Pacific time.

Mr. Jesus Quintero, Chief Executive Officer, will conduct one-on-one meetings during the conference and deliver the Company’s in-person presentation which can be viewed live and via replay at the webcast link below.

Event: LD Micro Invitational XII

Event Date: June 7 – 9, 2022

Location: Westlake Village, CA

MCOA Presentation Time: June 8, 2022, at 5:00 pm Pacific time in Track Four

Webcast: ldinv12.mysequire.com

Note: Interested parties who want to watch virtually must register on the platform. If you do no

Jesus Quintero, CEO will providt want to participate, please send an email to registration@ldmicro.com and let us know ahead of time.e updates on all MCOA initiatives, including its recent second consecutive quarter with record revenue growth. The Company expects its growth to continue to accelerate into the next quarter as MCOA continues to grow its business. Mr. Quintero will also discuss the Company’s activity in strategic acquisitions that fall into diversified cannabis categories as it continues to pursue deals to build scale in its existing markets. The Company also continues to look at opportunities that will grow its national footprint in the U.S., as well as in emerging markets such as Brazil and Uruguay.

About Marijuana Company of America, Inc.

Marijuana Company of America (MCOA) operates, invests, and acquires exclusively companies in the cannabis sector. The Company is a multi-state (licensed) operator and the parent company within the cultivation, distribution, and international consumer product sectors.

Summary of LD Micro Invitational (XII)

The 2022 LD Micro Invitational will be held at the Four Seasons Westlake Village from June 7th to the 9th. This three-day, investor conference is expected to feature around 200+ companies, presenting in half-hour increments, as well as private meetings.

Forward-Looking Statements

This news release contains “forward-looking statements,” which are not purely historical and may include statements regarding beliefs, plans, expectations, or intentions regarding the future. Such forward-looking statements include, among other things, the development, costs, and results of new business opportunities and words such as “anticipate,” “seek,” “intend,” “believe,” “estimate,” “expect,” “project,” “plan,” or similar phrases may be deemed “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995.

Actual results could differ from those projected in any forward-looking statements due to numerous factors. Such factors include, among others, the inherent uncertainties associated with new projects, the future U.S. and global economies, the impact of competition, and the Company’s” reliance on existing regulations regarding the use and development of cannabis-based products. These forward-looking statements are made as of the date of this news release, and we assume no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in the forward-looking statements. Although we believe that any beliefs, plans, expectations, and intentions contained in this press release are reasonable, there can be no assurance that any such beliefs, plans, expectations, or intentions will prove to be accurate. Investors should consult all of the information set forth herein and should also refer to the risk factors disclosure outlined in our annual report on Form 10-K, our quarterly reports on Form 10-Q, and other periodic reports filed from time to time with the Securities and Exchange Commission.

For more information, please visit http://www.marijuanacompanyofamerica.com or visit http://www.sec.gov.

CONTACT:

info@marijuanacompanyofamerica.com

info@mcoainvestments.com

888-777-4362

SOURCE: Marijuana Company of America Inc.

Thank you for consideration.
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NOOTROPICS: Hope or Hype?

NOOTROPICS: Hope or Hype?

The hot new trend in nutritional supplementation is NOOTROPICS, sometimes referred to as “smart pills” or “cognitive enhancers”. A nootropic is a substance capable of enhancing learning, memory, concentration, or other cognitive functions and of preventing or slowing cognitive decline. It is important to note that you do not need to have a medical issue to benefit from natural brain support. We all enjoy the feeling of functioning at the peak of our potential. The ability to think clearly, remember details easily, verbalize our thoughts articulately, sleep soundly, and handle stress with grace and ease, is priceless! These are all functions of a healthy brain in balance.

Whether you are a college student balancing a challenging academic schedule, a professional preparing for a big presentation, an executive competing for a big promotion, a mother juggling the management of a busy household, or a senior citizen desiring a quicker and sharper memory, NeuroSmart can give you the benefits you are searching for.

Synthetic prescriptions and over the counter drugs have been shown to be of limited benefit for enhancing brain function, while often causing troublesome side effects. However, a few high quality natural compounds have been shown, in clinical trials, to improve cognitive function. A handful of novel brain support supplements contain one or more of these valuable ingredients. Unfortunately, the actual amounts of legitimate nootropics contained in these products are usually miniscule. The extremely small quantities of scientifically validated ingredients are generally too insignificant to offer any real benefit. The list of ingredients might look good on the label, but they deliver no tangible results. In other words, all hype, no substance!

Scientific research is extensive and compelling. The brain is “hardwired” with specialized receptors for natural cannabinoids. Clinical studies indicate that neurogenesis (the production of NEW brain cells) is supported by premium hemp extracts and synergistic botanical compounds. This means there is the potential to enhance the building of new infra-structure in the brain.

NeuroSmart: A Game Changer with a Coveted U.S. Patent.

 

NeuroSmart exemplifies the practical application of cutting edge brain research. This unique ”first of its kind” product utilizes a synergistic blend of natural botanical compounds, in addition to Ayurvedic herbs, and premium broad spectrum hemp extract, all in scientifically researched amounts.

This innovative formula promotes optimal brain function in several fundamental ways:

  1. NeuroSmart supports the integrity of existing brain cells. Multiple Ayurvedic herbs and botanicals protect brain cells from assault by toxins, free radicals and inflammation.
  2. NeuroSmart supports optimal brain chemistry and neurotransmitter balance through the Endocannabinoid System.
  3. NeuroSmart promotes neurogenesis, the development of NEW healthy brain cells. This visionary synergistic atented formula supports the development of regenerative infrastructure in the brain.

In 2019, after nearly two years of in-depth analysis, the U.S. Patent Office awarded Patent # 10,201,553 to hempsmart’s revolutionary brain support formula, NeuroSmart. This excerpt from the U.S. Patent clearly illustrates the visionary application of scientific research in brain support:

“The present invention (NeuroSmart) is unique in that this product utilizes a synergistic blend of natural neuroprotective and neuroregenerative compounds, including cannabidiol (CBD), all in clinically researched and verified therapeutic amounts. Clinical studies indicate that CBD facilitates brain recovery from oxidative stress free radical damage and inflammation.”

“CBD research is extensive and compelling. The brain is “hardwired” with specialized receptors for CBD. Each ingredient in this invention has been clinically validated to provide a specific neuro-protective or neuro-regenerative effect.”

This important patent goes on to state:

“This unique formulation promises to revolutionize the safe and effective optimization of brain and neurological function.”

NO Hype, just Great RESULTS!

Unlike most brain support supplements on the market, NeuroSmart is a powerhouse of scientifically proven natural nootropic ingredients, in therapeutic amounts. The clinically validated ingredients include:

  • CBD – neurogenesis, neurotransmitter support, neuro- protection
  • Bacopa – neurogenesis, neuro-protection, memory, focus
  • Ashwaganda – stress reduction, cognition, memory, adaptogen
  • Phosphatidyl Serine – brain cell-to-cell communication, memory, concentration, learning, word choice
  • Alpha Glyceryl Phosphoryl Choline – neuro-protection, mental sharpness,
  • Rhodiola – short term memory, concentration, speed of mental processing, adaptogen
  • Huperzia Serrata – memory & learning enhancement, alertness, energy
  • Astaxanthin – protection from oxidative stress & inflammation
  • EGCG – memory, brain connectivity
  • Turmeric – neural stem cell growth, neuro-protection
  • L-Theanine – calming, mood enhancing

NeuroSmart supports:

  • mental clarity, alertness & cognitive processing
  • focus and concentration
  • relaxation & restorative sleep
  • ability to manage stress
  • learning and recall
  • repair, regeneration & plasticity of brain cells

Are you looking for peak performance in school, at work, or just in the day-to-day demands of multi-tasking? NeuroSmart offers a safe and effective solution.

 

Resources:

  1. Neurobiol Dis. 2009 May; 34(2): 300-7.
  2. Eur J Neurosci. 2013 November; 38(10):3424-34.
  3. Hussein G et al. (2005) Biol Pharm Bull. January; 28(1):47-52.
  4. Mar Drugs. 2016 March: 14(3), Epub 2016.
  5. Neurochem Int. 2009 March-April; 54(3-4); 199-204.
  6. Mol Nutr Food Res. 2015 Dec 8.
  7. Psychopharmacology (2014) 231:3879. Doi:10.1007/s00213-014-3526-1
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Happy Sativa Saturday, Indica, and Ruderalis HEMP? – Just What is Up?

As you dive deeper into the hemp world, you may encounter terms like cannabis strains, sativa, indica, or hybrid.

There’s a lot to know about this powerful plant, and we’re here to help educate you about the ins and outs of indica vs. sativa so you can make informed decisions about what you’re consuming on your wellness journey. The reason the different strains matter is because the indica vs. sativa effects vary due to the chemical makeup of those strains. We’ll go deeper into these differences in the section below. Are you curious about which strains are right for you? Continue reading to learn more. Some of the things we’ll touch on in this article are: Indica vs. sativa: What are they?

Indica effects Sativa effects What is cannabis ruderalis? Common Indica vs Sativa strains Choosing between Indica vs Sativa edibles. When most people think of indica vs. sativa, they think indica equals couch potato and sativa means energy. This isn’t always the case, especially as everyone’s body chemistry is different. Some indicas may be uplifting for some while some sativa strains may cause anxiety. There’s no “right way” to consume the different stains. It’s all about understanding the differences between the indica vs. sativa leaf so your approach to the plant is more well-rounded. You may be surprised to know that those terms don’t actually determine the effects, and are rooted in botany — the cannabinoid makeup and terpenes are what determine the effects of the strain. While this is true, the stereotypes about these different strains exist for a reason. If you’re ready to learn more about indica vs. sativa effects, keep reading. Indica vs. Sativa: What Are They? The terms indica and sativa are used to describe the different types of cannabis plant, along with cannabis ruderalis (which we’ll talk about a little later). The hemp plant is traditionally found in different parts of Europe and Central Asia. There were geographical barriers like the Himalayan Mountains that allowed for two different populations of the hemp plant to flourish — indica vs. sativa. When referring to indica vs. sativa leaf, people often mean the kinds that have a THC content above the federal legal limits. This is a narrow view of cannabis and hemp because products ranging from cannabidiol to any other hemp-derived product also comes from a specific strain. They often just get lumped into the category of “industrial hemp.” Indica vs. sativa is a way to help organize the thousands of different strains ranging from “Hindu Kush” to Maui Wowie. Now that you know a little about the origins of these types of hemp, let’s take a look at the indica effects, sativa effects, and their differences.

Facts About Cannabis Ruderalis cannabis ruderalis plant leaf

1) There’s A Reason It’s Named Cannabis Ruderalis If Cannabis ruderalis (C. ruderalis, or just ruderalis for short) were an animal, we’d call it feral — as in, living in a wild state. For plants, however, feral doesn’t apply. Instead, botanists use the term ruderal. Ruderal refers to a plant growing on waste ground, among refuse, and in extreme environments found in colder, more elevated climates. Essentially, ruderal describes a weed that grows where it’s not wanted and in competition with cultivated plants. So it’s not the slang sense you’re used to, but the actual scientific definition of a pesky, unwanted plant. Cannabis ruderalis commonly grows near roadsides, on agricultural land that is fallow, or on other land that humans have disturbed and then left alone.

2) Grew Originally In Russia And Adjacent Areas Cannabis ruderalis predates pretty much all of the countries you’d recognize on a map — meaning it was there before man put name to place. Scientists agree, though, that ruderalis was common in what is now Asia, Central and Eastern Europe, and specifically Russia. In fact, ruderalis probably originated in Russia and then spread east, west, and south into countries such as: Mongolia China Pakistan Afghanistan Kyrgyzstan Uzbekistan Kazakhstan Ukraine Slovakia Romania And others In many of these areas, ruderalis continues to grow as a weed in competition with more domesticated cultivars such as corn, wheat, and oats. Cannabis ruderalis isn’t very common in the Western Hemisphere because, as we’ll discuss, it’s only got one or two specific uses. For that and other reasons, humans didn’t go to the trouble of planting ruderalis here in the states.

3) Related To Indicas And Sativas Botanists include ruderalis as a third type of marijuana along with its relatives Cannabis sativa and Cannabis indica. That said, scientists aren’t really sure if ruderalis is a sibling or a cousin of the more common — and more widely used — varieties. In fact, they’re not even sure whether it qualifies as a species in its own right or if it’s a descendant of one of the other two. Genetically, Cannabis ruderalis falls somewhere between the indica and sativa strains, but its effects are quite different. Indica strains produce a lethargic and lazy body high rather than a head high. Because of that, indica’s benefits mostly deal with relief of conditions such as: Anxiety Stress Body pain Migraines Spasms Seizures Depression Nausea Sativa strains, on the other hand, produce an energetic head high that makes users feel more alert, creative, happy, and serene. Sativa strains are also notorious for their ability to make you hungry. As you’ll see later on in this article, Cannabis ruderalis does none of that.

4) The Smallest Of The Cannabis Plants Cannabis ruderalis is the smallest of the cannabis plants. While sativa strains grow up to 20 feet tall and indica strains grow up to six feet tall, ruderalis grows between one and two-and-a-half feet tall. Botanists attribute this small height to the fact that ruderalis needs to thrive in harsh and varied conditions, such as areas with poor soil, no shade, and exposure to winds and pests. A small, sturdy plant is much better suited to this type of environment than a tall plant. Because of its small stature, ruderalis is often referred to as dwarf cannabis or bonsai cannabis. Ruderalis produces only a few branches that contain wide, fat-bladed leaves. Ironically, the stereotypical pot leaf that has become a symbol of cannabis culture most nearly resembles the Cannabis ruderalis leaf. It’s ironic because ruderalis doesn’t get you high like sativa and indica.

5) Doesn’t Depend On Light Exposure To Flower Marijuana plants outdoors One of the most unique and valuable traits of the Cannabis ruderalis plant is that it doesn’t depend on light exposure to flower. Of course, ruderalis needs light to grow — as all plants do — but this strain doesn’t depend on the ratio of light to dark hours (the photoperiod) to switch from vegetative growth to flowering growth. Instead, the switch depends on age (i.e., number of days). Scientists call this trait autoflowering. What that means for the average grower — or the person who stumbles upon ruderalis in the wild — is that autoflowering strains don’t require varying the amount of light the plant gets the way you do with photoperiodic strains. Just to clarify, photoperiod-dependent strains (or photoperiodic for short) are your classic indica, sativa, and hybrid strains with names even the newest of noobs is probably familiar with (like Blue Dream, Sour Diesel, and Thin Mint Girl Scout Cookies). These strains respond to changes in light (i.e., the length of exposure) to “know” when to produce flowers. To better explain, think about the summer and fall seasons. During the longest days of summer, an outdoor plant might get 15 hours or more of sunlight. After the summer solstice, the number of hours of daylight decreases. This is usually the “cue” for plants to begin flowering. It’s the basic growing cycle that farmers have been dealing with for 11,000 years and that you probably learned about in kindergarten (only without the big words like photoperiod-dependent). The autoflowering ruderalis strain will grow for a certain number of days and then flower regardless of the amount of light it gets (as long as it gets enough to thrive, of course).

6) Grows Fast Cannabis ruderalis grows very fast. The typical lifecycle of a ruderalis plant — from seed to flower — is as low as 10 weeks (though 12 to 14 weeks is more typical). Compare that to the much longer grow times of indica and sativa — anywhere from four to six months — and you can see why breeders value this little plant.

7) Contains Very Low THC Levels The question on most people’s minds when it comes to Cannabis ruderalis is, “How much THC does this baby have?” Unfortunately, the answer is very little. How much is very little? It helps to compare ruderalis to hemp. To qualify as hemp — which is basically just a foodstuff and an industrial product — the plant needs to contain less than 0.3% of the cannabinoid THC. Cannabis ruderalis, on the other hand, typically exhibits less than 3% THC. That small amount is not enough to produce anything akin to a body or head high like indica and sativa (which can get as high as 28 or 29%)

8) Contains Some CBD Cannabis ruderalis does contain a bit of CBD, so you can use it to experience some wonderful medicinal benefits. The beneficial effects of CBD are legion, and more are being discovered every day. Here are some things CBD can do: Promote bone growth Inhibit growth in cancer cells Kill or slow bacterial growth Reduce risk of artery blockage Treat psoriasis Prevent degeneration of nervous system Reduce blood sugar levels Aid sleep Reduce seizures and convulsions Suppress muscle spasms Relieve anxiety Lessen the severity of psychosis Reduce nausea and vomiting Stimulate appetite Reduce inflammation Decrease pain For many patients, achieving these benefits without the psychoactive effects normally associated with marijuana would be like the holy grail of medical treatment. That’s one of the reasons Cannabis ruderalis is still used by many breeders: because mixing its genes with indicas and sativas is an easy way to increase CBD count without also increasing THC count.

9) Cannabis Ruderalis Is Not The Same As Hemp A bud of cannabis ruderalis Earlier in the article, we touched on one of the main differences between Cannabis ruderalis and hemp — THC levels. But there are many more differences between Cannabis ruderalis and hemp. Hemp is a relative of the sativa and indica plants that get you high, but growers have bred it in such a way that it’s extremely low in THC (0.3%). That’s so low you won’t feel a trace of psychedelia no matter how much you take — that’s why it’s been grown legally for decades. Similarly, hemp contains very low levels of CBD (0.5 to 2.0%) and other cannabinoids, such as CBG and CBN. So why grow it? Because it’s great as a foodstuff and an industrial product. Check any health food shop, “big box” grocery store, or corner bodega and you’ll likely find hemp seeds in there somewhere. Hemp seeds are high in polyunsaturated fats (omega-3 and omega-6), vitamin E, potassium, magnesium, and vitamins B1 and B2. This makes them a healthy addition to any balanced diet. We love sprinkling them in soups, salads, and smoothies for a delicious and nutritious kick. But the benefits of hemp don’t stop with the seeds. Manufacturers use hemp in everything from shampoo to plastics to paint to rope and clothing. It’s a very versatile plant! Cannabis ruderalis, on the other hand, is not a nutritionally dense plant, nor can it be used as an industrial product like hemp. Cannabis ruderalis is really only good for its genetics and its growing properties.

10) Doesn’t Need Your Help One of the nice things about Cannabis ruderalis is that it doesn’t need a lot of help from humans. As we touched on at the beginning of this article, it’s basically a weed (in the botanical sense) that’s going to grow despite your best efforts to the contrary. It’s very much like a dandelion in that regard. Have you ever had to feed and water and care for the dandelions in your front yard? Heck no! Those suckers just grow wherever they want. In fact, they’ll grow despite what you, mother nature, and even weedkillers thrown at them. Cannabis ruderalis exhibits many of those same characteristics. In fact, that’s one of the things breeders love about the plant — it exhibits a more laissez-faire attitude than some other, more needy and hands-on, strains of cannabis. Cannabis ruderalis is hearty, resistant to disease, grows in a variety of climates, and isn’t overly picky about the soil in which it lives. Sure, it’s got very low cannabinoid content, but its growing properties are extremely desirable.

Will Cannabis Ruderalis Get You High? Unless you’re an absolute newb and you’ve spent your entire life avoiding stimulants and psychoactives of every kind (including coffee, tea, pop, and high fructose corn sugar), Cannabis ruderalis will not get you high.

That said, we recommend taking things slow. Don’t jump from “never done it before” directly into the deep end. Increase the THC content slowly so you’re familiar with the feelings and know how your body will handle the high. To help you in this regard, here’s an incremental guide to help you answer the question, “Will get me high?” If your cannabis product contains one percent THC or less, you won’t feel a thing (because, most likely, this is hemp). If your cannabis product contains one percent to five percent THC, and depending on your pot experience, you might start to feel something (Cannabis ruderalis falls in this category). If your cannabis product contains five percent to 10 percent THC, you’ll probably hear a shape or two. If your cannabis product contains 10 percent to 15 percent THC, you’ll be well on your way to your HIGH. If your cannabis product contains anything above 15 percent THC, kiss reality goodbye.

If your cannabis product is (made from) a CBD-dominant strain used for medicinal purposes, you will not get high. So, again, will Cannabis ruderalis get you high? It will not. You might feel some medicinal effects (as in relief from anxiety or a decrease in pain if you have either) thanks to the CBD, but the very low THC content won’t be enough to give you the high that you’ve heard all your canna-pals talking about. Talk to the budtenders at your local dispensary and they can recommend a product with just the right amount of THC to keep you from getting too high. Is Cannabis Ruderalis Legal? A blunt with cannabis ruderalis In order to be completely, 100% legal, Cannabis ruderalis would have to exhibit the same traits as hemp. Specifically, that means that, in the United States, it would have to contain less than 0.3% THC (0.2%-0.3% THC in Europe).

As we discussed, Cannabis ruderalis typically contains 3% THC, which puts it well above the legal threshold. But, again, is Cannabis ruderalis legal? The answer is a bit confusing. Cannabis Ruderalis Is Not Legal At The Federal Level At the beginning of 2021, all cannabis is illegal according to the federal government. Currently, the Controlled Substances Act (CSA) of 1970 classifies cannabis as a Schedule I drug along with Heroin, Ecstasy, PCP, LSD, Psilocybin, Mescaline, and Peyote. Schedule I classification means that those substances have no defined medicinal purpose, have a lack of accepted safety under medical supervision, and have the highest potential for abuse. So, even though Cannabis ruderalis is about as harmless as you can get without becoming hemp, the federal government still lumps it in with much stronger drugs.

Cannabis Ruderalis Is Legal In Many States As of this writing, all 50 states have addressed the use of cannabis and cannabis-derived products (including Cannabis ruderalis). Here’s how it breaks down state by state. Legal Recreational And Medical Use Washington Oregon California Nevada Arizona Montana Colorado South Dakota Illinois Michigan Alaska Maine Vermont Massachusetts New Jersey Legal Medical Use Utah New Mexico North Dakota Minnesota Oklahoma Missouri Arkansas Louisiana Mississippi Florida Ohio West Virginia Virginia Pennsylvania New York Maryland Delaware Connecticut Rhode Island New Hampshire Hawaii

If the limit is below 3% THC, you’re golden and can partake of the Cannabis ruderalis with impunity. Cannabis Ruderalis Hybrids Are Perfect For Monster Cropping Weed plant

You’ll notice we didn’t say Cannabis ruderalis is perfect for monster cropping. It’s not.

First and foremost, it’s autoflowering.

Second, it doesn’t grow very tall and monster cropping works best on medium-height plants. Cannabis ruderalis hybrids — ruderalis mixed with an indica or sativa strain — however, are a different story entirely. If your hybrid fits the following characteristics, give monster cropping a try: Grows quickly and vigorously in the vegetative stage

Grows quickly and vigorously in the early part of the flowering stage

Grows lots of stems and bud sites

Grows to medium height Is not of the autoflowering variety Monster cropping is easy to do, doesn’t require a lot of plants to start, saves you money, and results in more flowers. An abundance of flowers, then, gives you more opportunities to toke with friends, to experiment with making your own cannabis products (e.g., hash, Thai sticks, cannabis coffee, cavi cones, and so much more), and to perfect your growing process so you can produce the best buds for recreational or medicinal use. Despite those benefits, monster cropping with Cannabis ruderalis hybrids is not without its drawbacks.

You’ll definitely need more space — one for the parent plant and one for the new plant(s) — and the ability to regulate conditions such as humidity, airflow, temperature, and light in each. Y

ou’ll also add two to three weeks to the grow cycle so that the plants can revegetate. If you’re in a terrible rush, you may want to buy your weed at a dispensary while the plants grow, or skip monster cropping altogether until you’ve got more time to spare. It’s also worth noting that not every cutting (clone) will grow.

No one knows why and it’s one of the great mysteries of the universe (right up there with a unified field theory). It’s just something you have to accept if you venture down the monster-cropping road.  When it comes to cannabinoid content, Cannabis ruderalis is close to the bottom of the barrel. C. ruderalis is very low in THC — so it won’t get you high — and, though it does have some CBD, you won’t feel the same quality of medicinal effects because the concentration is lower than high-CBD indicas and sativas.

Similarly, Cannabis ruderalis has very little value as a foodstuff or an industrial product.

Unlike hemp, ruderalis isn’t high in vitamins and minerals. And manufacturers can’t use it to produce chemical or textile products like shampoo, lotion, soap, plastic, paint, rope, or clothing.

The true value of Cannabis ruderalis lies in its abilities to autoflower and to grow quickly. For years, breeders have crossed common cannabis strains with C. ruderalis to improve growing time and flowering without decreasing cannabinoid content. So, while Cannabis ruderalis is pretty much just a weed, the fact that it will grow nearly anywhere — and do so quickly and without a lot of human interference — makes it a valuable member of the cannabis family.

 

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Planting The Seeds of CDB . . .

An entire industry is being built around cannabidiol, or CBD,  

one of the many chemical constituents of the cannabis plant.

 

A message from the Founder of “Inspirational Technologies

      Inspirational Technologies – Steven Smith 2021                            In this Blog,                                             “Planting the Seeds of CBD . . .”,           we wish to Inspire those who are still waiting for the process of “Legitimizing the Claims of CBD” and “MOVE  the CHAINS” forward in the game of CBD. We have had patience, waited on government regulators and Pilot Hemp Programs to give framework to the farmers, cultivators and processing plants. Thank you for your participation, Steven M Smith, Owner/Founder, Inspirational Technologies.

 

Advocates of the compound say it confers all sorts of health benefits,

from mitigating the symptoms of depression and anxiety to treating Glaucoma,

 

 

It’s cropping up in protein powders, bath salts, makeup and even jelly beans.  

 

Medical Advisory Groups for Corporate Subsidiaries are critical for US FDA CBD Compliance

 

But scientists are still unsure of exactly what the benefits — and pitfalls — of CBD are. 

“Society has jumped way ahead of the science on this,” said Margaret Haney,

a professor of neurobiology at Columbia University Medical Center in New York.

Reported benefits have mostly been anecdotal, or they have come from studies involving animal models.

CBD isn’t well understood, nor have there been sufficient studies done in humans, she said.

 

 

Cannabis plants produce a group of chemical compounds called cannabinoids.

The best-known are tetrahydrocannabinol, or THC

(the so-called psychoactive component of the plant that’s associated with the marijuana “high”),

and CBD (a non-intoxicating component of the plant that doesn’t produce a high),

Hemp. Recently, Legal to grow and process for CDB.  

 

Florida Hemp 2019

 

 

Here’s what we do know: CBD can help treat some types of pediatric seizures.

Last year, the FDA approved GW Pharmaceuticals PLC’s Epidiolex for the treatment of seizures associated with two rare forms of epilepsy in patients two years of age and older.

But, to get to that point, GW Pharmaceuticals had to go through a long and rigorous drug-approval process to show the drug’s safety and efficacy through clinical trials.

This hasn’t been done with CBD for any other indication, until now.

While it’s true that CBD has shown promise in pre-clinical and animal trials in addressing a number of issues such as pain, anxiety, neuroinflammation and substance-use disorder,

there’s still not nearly enough peer-reviewed research available, said Ziva Cooper, research director of the Cannabis Research Initiative at the University of California, Los Angeles.

To truly determine the effects of CBD in humans, many further studies need to be done — studies with humans, she said. “Overall, we have very little real data on the therapeutic effects of cannabidiol,” she said.

As for those CBD-based skin products that are popping up on shelves and online, Columbia University’s Haney said she remains skeptical of their marketed benefits.

Many are diluted. It’s a question of both dosage and absorption, she said. “We have no idea how much CBD you would need to rub on your skin for it to have some kind of medical effect,” she said.

 The amount of CBD in a lot of marketed products — even ones that are meant to be taken orally — is so small that we can not make any therapeutic measures for the person using it, said UCLA’s Cooper.

In the few studies that have involved humans, doses were in the hundreds of milligrams, but most CBD-infused products contain much less than that,

which the company says can be used as a daily supplement and help “promote a calm sense of well-being,” it also notes on its website that such statements “have not been evaluated by the Food and Drug Administration.”  

CBD advocates were hoping laws around the compound might loosen up — or at least become clearer — after President Donald Trump signed the 2018 Farm Bill.

Hemp Is Now A Viable Agriculture Phenomenon

 

The bill legalized hemp, a variety of the cannabis plant that contains no more than 0.3% THC.

December 2018 – The Farm Bill Legalized Hemp

But regulation of CBD, whether derived from hemp or not, is still largely under the FDA’s jurisdiction.

Since CBD is technically an active ingredient in an FDA-approved drug,

companies are not allowed to add it to food or drinks sold across state lines or to sell it as a dietary supplement.

 

Companies are, however, allowed to put the compound into beauty and skin-care products, as cosmetics are not subject to premarket approval by the FDA.

That could explain why drugstore chains like CVS and Walgreens aren’t worried about introducing CBD-infused topical products in their stores.

“People shouldn’t confuse availability with legality,” said former FDA regulatory counsel Jonathan Havens.

The agency has cracked down on unfounded claims, but it has limited resources and can’t get to everyone, so it is focusing mostly on companies making blatant health claims about their products, Havens said.

 

The FDA recently sent warning letters to Advanced Spine and Pain LLC, Nutra Pure LLC and PotNetwork Holdings,

saying the companies violated federal law by advertising their CBD-containing products as potential treatments for ailments including cancer, Alzheimer’s disease, arthritis and more. 

“The FDA wants to protect consumers. The last thing it wants is companies out there marketing CBD products and claiming health benefits without any clinical research to validate that,”

said Rob DiPisa, co-chair of the Cannabis Law Group at law firm Cole Schotz. 

US FDA Fight to Regulate Cannabis (Hemp) More Research is Needed

At the same time, requiring anyone who wants to put a CBD-containing food or beverage on the market to go through the clinical-trial process would “chill the whole CBD market,” he said.

  The FDA is aware of the public’s interest in CBD. Former FDA commissioner Scott Gottlieb put out a statement outlining steps to figure out a framework to lawfully market cannabis

and cannabis-derived products, including  public hearings and formed an internal working group to look into the issue.

DiPisa said he hopes the hearings last  May 2021 will provide more clarity for him and his clients.

“Everyone is running blind right now,” he said.

 

 

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Current State Of CBD and Cosmetics in the USA

Although the current state of regulation for CBD is in-flux for supplement and food products, the outlook is pretty good for beauty, as long as companies are careful about where they source the CBD, otherwise adhere to the regulations governing the marketing of cosmetic products, and limit sales to states where the sale of such products is legal.

While CBD Infused Beverages and Food Remains with the FDA. Cosmetic Use Is An Open Market Soon To Be Saturated.

  CBD, or Cannabidiol, is one of many cannabinoids found in the plant species Cannabis sativa L., which, surprising to many, includes marijuana and hemp.

December 2018 – The Farm Bill Legalized Hemp

The 2018 Farm Bill defines hemp as any part of the plant Cannabis sativa L. with a THC concentration of not more than 0.3% on a dry weight basis, and removes hemp and hemp derivatives from Schedule I of the Controlled Substances Act. CBD derived from a marijuana plant, or from a hemp plant with a THC concentration of greater than 0.3%, fall outside the statutory definition of hemp and therefore remain controlled substances. In order to legally market beauty products containing CBD, companies must be able to establish that the ingredient is derived from a hemp plant, grown by a licensed grower, and contains 0.3% or less THC. The United States Department of Agriculture, the regulatory agency responsible for implementing the 2018 Farm Bill, issued a legal opinion confirming that states may not prohibit the interstate transportation of hemp or hemp derived products that satisfy these requirements.

Department of Agriculture (USDA)

The Farm Bill does not, however, supplant the Food, Drug and Cosmetics Act (“Act”). Under the Act, companies that want to market beauty products containing CBD cannot claim the products, or the CBD, is intended to affect the structure or function of the body, or otherwise treat, mitigate, or prevent a disease. In addition to these Federal regulatory requirements, companies must also adhere to the laws of individual states, which have the right to restrict or limit the sale of CBD products within their jurisdictions. Thus, before shipping a CBD beauty product, companies should confirm the sale of such products is legal in the target state.

Nikki Fried -Florida Agriculture Commissioner 2021

  Why is it crucial for CBD brands and ingredients providers to be completely up to date on the fast-changing regulations? The fast-changing regulations really have to do with growing and licensing requirements for hemp growers. The regulation of what constitutes legal hemp is pretty much set by the 2018 Farm Bill. Since CBD derived from hemp is the only ingredient that has been legalized by the Bill, it is critical for companies and ingredient suppliers to be sure (1) the hemp is sourced from a licensed grower, and (2) the THC content is 0.3% or lower.

3rd Party Certificates Of Analysis (COA) determine what is in the sample tested. Look for the Good and the Bad. *Pesticides, Heavy Metal or Added Toxins. COA’s are a necessity.

  Products that fail to meet these two requirements fall outside the statutory definition of hemp, fall within the definition of marijuana under the Controlled Substances Act, and are thus illegal.

Florida Hemp

Companies interested in marketing and selling CBD cosmetic products will gain insights into the regulatory landscape surrounding the marketing of such products, and in particular, have an understanding of the FDA’s and FTC’s current thinking and approach to regulating the products. Research strategies companies can follow to avoid attracting the attention of regulators and consumer lawyers.   What is the number one question that CBD beauty professionals have? There are really two questions to answer. The first is can we legally sell cosmetics containing CBD? The second question is what can I do to protect the company from claims arising from the sale of CBD beauty products. As noted in response to question 1) above, the question of legality is somewhat straightforward. The question of protection is more complex, and involves the need contract with vendors, secure insurance coverage, and consider a myriad of other business considerations.

“Misunderstood”   The Hemp Story

  House Appropriations Committee to Consider Hemp Guidelines this Summer.

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