Category: Hemp News

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180 Life Sciences Corp. has selected a lead synthetic CBD analogue that is expected to move forward in clinical development.

MENLO PARK, Calif., July 28, 2021 180 Life Sciences Corp, a clinical-stage biotechnology company focused on the development of novel drugs that fulfill unmet needs in inflammatory diseases, fibrosis and pain, announced today that it has selected a lead Synthetic CBD Analogue that is expected to move forward in clinical development for both inflammation and pain.

As part of a continuing collaboration since 1998 with the pioneer of cannabis chemistry, Raphi Mechoulam (Hebrew University, Jerusalem), Sir Marc Feldmann’s (the Company’s Co-Executive Chairman and Co-Founder) laboratory, and 180 Life Sciences’ scientists, identified the non-psychoactive CBD analogue as a lead molecule in the Company’s SCA platform.

The analog was selected based on a wide-ranging screen of derivatives of cannabidiol and cannabigerol made by Prof Mechoulam.

The Company believes that the analog appears to have (1) a novel composition of matter which would enable patent protection, (2) robust preclinical efficacy in several established mouse models for treating pain and inflammation in vivo , and (3) ease of scalability for future good manufacturing practice (GMP) manufacturing. Its safety profile is being explored in greater detail.

Dr. James Woody, 180 Life Sciences’ Chief Executive Officer, stated, “We believe that our lead compound HUM-217, a CBD derivative generated by cannabis chemistry pioneer Prof Raphael Mechoulam, meets all the criteria desirable to advance to clinical development. We look forward to continuing to pursue new therapeutics for one of the world’s largest drivers of disease, Inflammation.”

Prof Sir Marc Feldmann, 180 Life Sciences Executive Co-Chairman added, “It is a real pleasure to announce the progress that has been made, which we believe is a significant step forward towards the more effective use of pure synthetic cannabinoids in medicine. We look forward to continuing the development of these compounds in clinical trials.”

*About 180 Life Sciences Corp. 180 Life Sciences Corp. is a clinical-stage biotechnology company focused on the development of novel drugs that fulfill unmet needs in inflammatory diseases, fibrosis and pain by leveraging the combined expertise of luminaries in therapeutics from Oxford University, the Hebrew University and Stanford University. 180 Life Sciences is leading the research into solving one of the world’s biggest drivers of disease – inflammation. The Company is driving groundbreaking studies into clinical programs, which are seeking to develop novel drugs addressing separate areas of inflammation for which there are no effective therapies. The Company’s primary, most advanced platform is a novel program to treat fibrosis using anti-TNF (tumor necrosis factor) which is in the clinic.

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CBD Honey? No Really, May Bee the Solution.

“Hemp is a high pollen producing crop flowering during a period of floral resource scarcity and supports a diverse array of bees in the northeastern U.S. landscape.”

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In a new study published in the journal Environmental Entomology, researchers in the Department of Entomology at Cornell University in New York wondered if the growing legalization of cannabis for recreational, medical and industrial purposes is having any effect on bees.

See the source image

While marijuana is becoming in New York, industrial hemp is a fast-growing industry and the flowers are essentially the same. In a simple test (repeat visits to New York hemp farms and collected bees with nets), the researchers found 16 different bee species happily buzzing around the buds.

That variety highlights the “species richness” of Cannabis sativa when it comes to attracting bees.

“Industrial hemp offers a unique floral resource to bees in agricultural landscapes. Hemp flowers late in the summer releasing an abundance of pollen during a period of native and agricultural floral dearth. As a result, hemp pollen may offer a vital subsistence resource to bees at a point in the season when they are resource-limited, thereby helping to alleviate the pressures imposed by spatial and temporal variation in resource availability that is characteristic of simplified agricultural landscapes.”

The researchers weren’t as concerned about the growing creation of cannabis honey (we know you are – hang on) as much as how the dominance of cannabis would affect the bees.

It turns out that besides being attractive to a diversity of bees, cannabis blossoms in the late summer when most other plants are finished and bees are looking for pollen. By extending their season, cannabis may actually be helping to strengthen the bees to fight off the diseases that have decimated their populations in recent years. What about the cannabis honey?

Right.

Most products labeled cannabis honey are actually infused with CBD or THC.

While beekeepers claim the honey from bees specializing in cannabis flowers contains cannabinoids, it’s tough to differentiate between benefits that might come from them and the natural benefits of honey.

The Israeli cannabis technology company PhytoPharma International is offering pure, non-infused, highly bioavailable cannabis-derived honey called Pure Bee.

It’s available in two forms — non-intoxicating CBD Honey and psychoactive THC Honey – and is said to take effect in 10 minutes, much faster than most edible cannabis products.

So, do bees really get a buzz from marijuana? Unfortunately, no. Bees lack cannabinoid receptors and merely pass them on to their honey.

They buzz the buds merely for the fun and the exercise.

That’s just another good reason to be kind to bees.

 

 

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8 – 8 – 2021 Happy CBD Day! From Inspirational Technologies

About National CBD Day The CBD industry celebrates National CBD Day on August 8 every year.

 The CBD community continues to commemorate CBD Day, which focuses on educating and creating awareness about CBD among consumers through media coverage and social media.

Issues covered include ongoing studies, CBD uses, and its benefits. However, CBD brands also provide deals to enjoy during this holiday.

 

CBD is a derivative of hemp, which has faced its share of political problems, with leaders banning its use.

The hemp plant has been around for centuries, with growers using it for fiber and other things. However, it was until 2018 that hemp became legal federally.

The 2018 Farm Bill that became law recognizes hemp as legal if it has 0.3% THC or less.

The CBD industry continues to gain popularity as more people learn of CBD’s potential wellness benefits.

 

Today, you can utilize CBD in a variety of ways. Users can consume CBD in the form of oil or capsules or choose delicious gummies, which come in various mouth-watering flavors.

Brands also provide CBD topicals like creams and salves that offer targeted relief on affected body parts only.

However, preliminary research has shown CBD to help with pain, stress, anxiety, and inflammation, among other benefits. However, more studies are needed to provide additional data on CBD’s capability to alleviate such health conditions and others.

 

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Six Steps To Better Sleep

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SIX WAYS TO BETTER SLEEP

If you’re like one of the millions of Americans who struggle to get restful sleep, consider implementing these steps into your bedtime routine. Hempsmart Smart Drops are a great addition to your sleep routine, helping you achieve more restorative sleep and overall well-being. hempsmart™ hempsmart™ hempsmart™ is committed to using only the highest quality all-natural ingredients, cutting edge science-based formulations, and premium broad-spectrum hemp extracts in therapeutic amounts to formulate our product-lines with a sophistication and effectiveness beyond compare. It is our goal to help transform personal health into planetary health.

If you’re like one of the millions of Americans who struggle to get restful sleep, consider implementing these steps into your bedtime routine. 

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It is our goal to help transform personal health into planetary health.

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House Appropriations Committee to Consider Hemp Guidelines this Summer.

Watching Florida's Stop Light on Marijuana

Earlier this summer, representatives in the U.S. House began working to reconsider policies, extend compliance times and clarify regulations for hemp production and consumption in the United States.

On June 30, 2021, the House Appropriations Committee advanced several hemp-related legislative items. In a report issued by the committee, industrial hemp production and marketing was deemed “an especially important opportunity for rural communities.”

The same committee urged the U.S. Dept. of Agriculture (USDA) to clarify that hemp-related businesses should be eligible for all rural agricultural grants. “The intent of Congress in Public Law 115-334 was for industrial hemp to be eligible for all USDA programs, including Rural Development,” the committee report stated.

Department of Agriculture (USDA)

The report continues, “Industrial hemp can significantly benefit struggling rural economies. The Committee encourages Rural Development to ensure that industrial hemp is eligible for all competitive grant programs.” The committee also proposed a significant increase in agricultural funding with $16.7 million earmarked to support the federal hemp production program.

This is the same amount listed in the Fiscal Year 2022 budget proposed by Pres. Biden. The House Appropriations committee also included a recommendation to USDA and DEA for more clarification and coordination on the regulation of hemp extract.

The report stated that “the Committee directs USDA to coordinate directly with the DEA to present the industry with guidance and information on in-process extracted material” to address specific concerns brought up by hemp industry stakeholders.

December 2018 – The Farm Bill Legalized Hemp

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NPE of Cannabis Global Updated Product Launches 🚀

Cannabis GlogalCannabis Global Prepares for Premium Cannabis Product Releases

LOS ANGELES, CA -June 10, 2021 – Cannabis Global Inc., the majority owner of licensed cannabis manufacturer Natural Plant Extract (NPE) and Northern Light Distribution, a licensed cannabis distribution company, today provides a business update regarding upcoming product launches. NPE, based in Lynwood, California, has completed its first round of compliance testing and is preparing for the June introduction and shipment of several new products.

The products will include super premium, THC-A Diamond, Live Resin-infused cannabis pre-rolls, a new line of vegan, stevia-enhanced cannabis candy products, and top-shelf cannabis flower products based on indoor grown strains. “In crowded, highly competitive Southern California, we need to have unique products, and that is exactly what we have created,” commented Cannabis Global CEO Arman Tabatabaei. “Among other products on deck, our premium diamond-infused pre-roll product will be a leader in potency with our first introduction topping 45% levels of THC (tetrahydrocannabinol). With a unique infusion manufacturing process and a hand-finish that allows for even concentrate distribution throughout the pre-roll, we are able to achieve both ultra-high potency and an ultra-smooth smoking experience.

“The Company will also introduce its all-natural, vegan, cannabis-infused Pate de Fruits candy line designed to compete at the premium end of the cannabis edibles market. Pate de Fruits is made from real fruit purées, a stevia-based sweetener blend, and other “best available anywhere” ingredients. Its heat-resistant design is expected to be especially attractive to cannabis delivery companies, which often struggle with melting of edible products during the warmer months of the year.”

“We are confident that cannabis consumers and our investors will be impressed with our new products,” Tabatabaei continued. “We have undoubtedly taken a product track toward ultra-premium products, as we believe this underserved area shows increasing consumer interest. We have also significantly increased our distribution business via our Northern Lights distribution company, which is co-located at our Lynwood, California, facility. Additionally, we are diligently working to complete our volatile extraction laboratory in conjunction with our project investment partner, Marijuana Company of America.

Excerpts from News Release 2021

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