Category: Noteworthy Inspirations

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UN Commission on Narcotic Drugs Votes to REMOVE Cannabis and Derivatives From Schedule IV

December 2020

 Up until this month, cannabis and derivatives of cannabis have been maintained in Schedule IV of the 1961 UN Single Convention on Narcotic Drugs. This schedule is for those drugs which have a high potential for abuse and harm and extremely limited medical use, such as fentanyl and heroin. In January of 2019, the World Health Organization’s Expert Committee on Drug Dependence made six recommendations to be voted on by the UN for subsequent adoption. After a number of delays, the United Nations Commission on Narcotic Drugs convened for their 63rd session today to vote on whether or not to adopt the recommendations. The recommendation with the most significant support leading up to the vote, and with far reaching consequence for international control of cannabis is the first recommendation 5.1,

The United Nations Commission on Narcotic Drugs (CND) on Wednesday accepted a World Health Organization (WHO) recommendation to remove cannabis and cannabis resin from Schedule IV of the 1961 Single Convention on Narcotic Drugs.

The historic vote in Vienna could have far-reaching implications for the global medical cannabis industry, ranging from regulatory oversight to scientific research into the plant and its use as a medicine.

 

This means that cannabis and its derivatives are now maintained in schedule I rather than being in schedule I and IV. This is a major win for cannabis advocates around the world with considerable symbolic and some practical implications for cannabis regulation. Removal of cannabis from schedule IV means that the UN accepts the opinion of the WHO that cannabis is not “liable to produce ill-effects” on the scale of other drugs in Schedule IV, and that cannabis has significant potential therapeutic value. The fact that cannabis remains in Schedule I means that it is still subject to strict international control, so the immediate legal consequences for the regulation of cannabis are limited. However, in the words of the US representative at the vote Ethan Glick: “This action has the potential to stimulate global research into the therapeutic potential and public health effects of cannabis and to attract additional investigators to the field including those who may have been deterred by the Schedule IV status.” (Previous version of the schedule) CBD will not be removed from international control Recommendation 5.5 has been rejected by a majority of 43 votes against, 6 for and 4 abstentions, meaning the UN will not “Add a footnote on cannabidiol preparations to Schedule I of the 1961 Convention to read: Preparations containing predominantly cannabidiol and not more than 0.2 percent of delta-9- tetrahydrocannabinol are not under international control”. This means that CBD will remain in some legal ambiguity under the UN conventions. It is likely that many nations who voted against the bill were not against the liberalization of CBD in principle but may not have agreed with the specific recommendation. For example, the representative of Colombia Miguel Camilo Ruíz Blanco told the commission that “Colombia’s negative vote is based on the absence of clear language in these recommendations” rather than a principled opposition. The US took the position that this recommendation was not needed as “It is not our position that CBD is under international control under the drug conventions” as it is not specifically mentioned in relevant legislation. It is likely that individual regions will continue to apply their own interpretations of the place of CBD in international control. Just last week, the highest EU courts determined that the 1961 Convention does not implicate CBD in international narcotics control. Other recommendations The other four recommendations made by the WHO were rejected by the majority of the 53 member states who voted. Recommendation 5.2.1 would have added THC specifically to Schedule I, entailing some rearrangement of international controls without a significant loosening of restrictions on its use. Recommendation 5.2.1 was rejected by a majority 28 votes against and 23 against. This has the consequence that THC is not moved to Schedule I of the 1961 Convention. Furthermore, on the basis of the rejection of this motion the recommendations 5.2.1, 5.3.1, 5.3.2 and 5.6 were automatically rejected as these were contingent on the passing of 5.2.1. Recommendation 5.4 which would “Delete extracts and tinctures of cannabis from Schedule I of the 1961 Convention” was rejected with 27 votes against and 24 votes in favor

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CBD will not be removed from international control

Recommendation 5.5 has been rejected by a majority of 43 votes against, 6 for and 4 abstentions, meaning the UN will not “Add a footnote on cannabidiol preparations to Schedule I of the 1961 Convention to read: Preparations containing predominantly cannabidiol and not more than 0.2 percent of delta-9- tetrahydrocannabinol are not under international control”. This means that CBD will remain in some legal ambiguity under the UN conventions. It is likely that many nations who voted against the bill were not against the liberalization of CBD in principle but may not have agreed with the specific recommendation. For example, the representative of Colombia Miguel Camilo Ruíz Blanco told the commission that “Colombia’s negative vote is based on the absence of clear language in these recommendations” rather than a principled opposition. The US took the position that this recommendation was not needed as “It is not our position that CBD is under international control under the drug conventions” as it is not specifically mentioned in relevant legislation.

                         

 

 

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Edibles Now Legal in Florida – Cookie Monster Happy

Reposted from September 9th, 2020  

Florida Edibles will account for more than 40% of Medical Marijuana Sales if Colorado is any indicator.

The Florida Department of Health has officially issued production standards, meaning dispensary sales of marijuana edibles are now legal!

September 2020 Brings Edibles To Florida Medical Patients
To check out the official production standards for edibles issued by the Florida Department of Health, see: Final Standards for Production of Edibles.
And for everything else you need to know about marijuana edibles, keep reading below!
WHY DO PEOPLE LIKE MARIJUANA EDIBLES?
As both medical and recreational marijuana become legal in a growing number of states, so too does the popularity of edible forms of cannabis. Data from Colorado, which was among the first states to legalize marijuana, indicates that edible cannabis-infused products account for some 45% of all cannabis sales. (These figures do not include homemade A nationally representative study of adult cannabis users reported that nearly 30% of all users had consumed cannabis in edible or beverage forms. Because these figures represent users who obtain marijuana products through both legal and non-legal sources, it is likely skewed towards combustable rather than edible products, as smoked marijuana is more easily obtained in areas where sales are not yet legal.

In Canada, where both smoked and edible forms of cannabis are legal on a national basis, a 2019 study indicated that over 25% of all users preferred edibles. It has also been shown that individuals using cannabis for medical purposes are more receptive to edible products, and that edibles are more popular with older adults.

For patients who are unable to receive inhaled cannabis medications due to conditions such as asthma and COPD, or who simply dislike the taste of burnt marijuana, edible forms of the product provide a viable alternative.

The generally perceived benefits of edible cannabis include:

  • The ability to deliver measured dosages
  • A longer duration of effects as compared to smoking or vaping
  • No need for additional equipment such as vape pens or pipes

A 2016 peer-reviewed manuscript on the subject outlined several additional potential benefits of edible cannabis:

Anecdotal reports attribute increased interest in edibles to several perceptions shared by users: (1) edibles are a discreet and more convenient way to consume cannabis; (2) edibles offer a “high” that is calmer and more relaxing than smoking cannabis; and (3) edibles avoid the harmful toxins and health risks that come with smoking cannabis.

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CBD Research Studies The ” C ” Word


Recently my research has found this interesting documentation about canabis oil (actual Full Spectrum CBD in independent studies.)

Inspirational Technologies – 2020 AllRightsReserved

Just fell over this – a little research documentation regarding Cannabis and cancer…. I decided to post the complete studies myself. Undergoing my secondary verifications 😊 😃.

′′ Therapeutic cannabis oil and its carcinogenic methods
There are cannabinoids that have anti-tumor properties such as THC and CBD, among others. In preclinical models, it has been possible to demonstrate antitumour activity in different types of tumours such as brain tumors (Gliomas), Skin (Melanoma and Kutan-Squamous cell carcinoma), chest, pancreas, liver and prostate tumours, among others (Munson y cols., 1975; Galve-Roperh cols., 2000; Velasco y cols., 2012; Velasco y cols., 2016).

The cannabinoids activate CB1 and CB2 receptors present in the tumour cells, thus initiating a complex route of intracellular signalling that causes cells to die (Carracedo y cols., 2006; Salazar y cols., 2009 ; Velasco y cols., 2012; Hernandez-Tiedra y cols., 2016).

In addition to causing the tumour cells ′′ suicide “, cannabinoids also inhibit the excretion of VEGF factor needed to form the cancer’s blood vessels. This means that nutrients necessary for growth of tumour is blocked (Blazquez y cols., 2003; Blazquez y cols., 2004).

A third antitumor effect is the cannabinoids ability to modulate the effect of certain enzymes (Metalloproteases) involved in remodeling the extracellular matrix, which is an important aspect of the ability to migrate and invasion of the tumour (Blazquez y cols., 2008; Velasco y cols., 2012; Velasco y cols., 2016).

In addition to the direct effects on the tumour and its growth, cannabinoids can provide beneficial effects as an adjuvant treatment for some types of tumours (cerebral gliomas). Animal studies have shown that cannabinoids can enhance both chemotherapy (Torres y cols., 2011) and radiotherapy (Scott y cols., 2014).

In the palliative treatment (non-curative symptomatic treatment) of tumours, cannabinoids improve many symptoms that occur frequently during chemotherapy such as nausea, vomiting, loss of appetite, physical pain or insomnia ′′

 

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Pet Owners Have found “Fireworks Secret” – CDB Pet Drops

Just as some CDB Users have found comfort in CDB Drops, some pet owners are turning their attention to CBD products to help calm their pets during the fireworks.

Two-year-old Smoky is a playful husky, but when it comes to the loud boom of the fireworks on the 4th of July, his owner tells us he tends to get skittish.

“Even last night there was only like two or three that went off and he was running afraid of and trying to hide under me and my bed,” said a customer in the store.

The customer says she’s tried everything from turning up the music and TV to even giving her pets a sedative to calm them during the 4th of July.

That’s why some pet owners are looking at CBD, a hemp-based product typically used to treat pain and anxiety in people.

There are many places that sell CBD, that not only sells products for people to use but ones for pets, too.

A local owner, has been selling CBD products for the last two years, and he’s already sold out of dog treats for the 4th of July.

He says the CBD oil can be added to their food, water, or a droplet can be given to a dog behind their tongue.

“So they’re going to be more relaxed, you’re going to see them maybe laying down, not as intense, they’re not going to as on edge as they were before taking CBD,” said the owner.

He says CBD is safe for pets as long as they follow the appropriate dosage on the label. You also want to make sure it was made in the U.S. and you know what’s in it.

“You have to be careful you don’t mix certain additives with the CBD oil, for example like peppermint is toxic for animals so you want to stay away that,” said the owner.

This year a shopper in his shop said she may consider giving her dog CBD. 
 
“The oil’s probably a little healthier for them in the long run I would say, if it helps calm them down a little bit and they’re less afraid of the fireworks, I might as well give it a try,” said the shopper.

We at “Inspirational Technologies” recognize that many pet owners and are looking for a quality “CBD” (THC Free) for their pets and themselves. That is why we are promoting this product and recommend  that you give it a try.  

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Scientists Just Learned How CBD Makes Molecules 30x More Effective Than Aspirin. Why Opioids Just Can’t Compete.

Cannabis is a complex plant with a complex history. It’s been cultivated for at least 6,000 years, but because of its modern legal status, we’re still learning new things about its medicinal benefits.While most of us have heard of the plant’s pain-relieving cannabinoids, such as CBD, there’s a lesser known class of compounds that deserves our attention.

Flavonoids are a group of natural substances that are thought to hold anti-oxidative, anti-inflammatory, and anti-carcinogenic properties. These compounds are found in fruits, vegetables, flowers, tea, wine, and, yes, even cannabis.

In 1986, researcher Marilyn Barrett at the University of London was the first to identify two cannabis flavonoids, known as cannflavin A and cannflavin B, both of which were found to have anti-inflammatory benefits 30 times more effective than Aspirin.

But while the flavonoid pathway has been extensively studied in several other plants, for decades, there has been no specific data on their biosynthesis in cannabis. Now, for the first time, researchers in Canada have uncovered how the cannabis plant creates these important pain-relieving molecules.

Our objective was to better understand how these molecules are made, which is a relatively straightforward exercise these days,” explains Tariq Akhtar, a molecular and cellular biologist at the University of Guelph.

“There are many sequenced genomes that are publicly available, including the genome of Cannabis sativa, which can be mined for information. If you know what you’re looking for, one can bring genes to life, so to speak, and piece together how molecules like cannflavins A and B are assembled.”

Using a combination of genomics and biochemistry techniques, the team was able to pinpoint which genes were responsible for creating these two cannflavins. Their findings provide the first evidence of a unique genetic pathway in Cannabis sativa plants, which uses two enzymes to ultimately create cannflavin A and B.

Extracting and purifying these compounds from a cannabis plant, however, just isn’t practical. Akhtar epxlained to The Toronto Star that these cannflavins only make up about .014 per cent of the plant’s weight, so fields and fields of cannabis would have to be grown in order to capture these anti-inflammatory benefits.

As a result, the researchers hope to use this new information to metabolically engineer their own pain-relieving medicine outside of the cannabis plant. To achieve this, they will be working with the Toronto-based company, Anahit International Corp., which has already licensed a patent from their university.

“The problem with these molecules is they are present in cannabis at such low levels, it’s not feasible to try to engineer the cannabis plant to create more of these substances,” says co-author Steven Rothstein, who studies the molecular and genetic qualities of crop plants at University of Guelph.

“We are now working to develop a biological system to create these molecules, which would give us the opportunity to engineer large quantities.”

Without some of the side effects of other painkillers, the authors think the synthesis of these molecules could make a big difference in the pharmaceutical industry.

Previous studies have shown that the vast majority of patients prefer cannabis to opioids when managing their pain, which suggests there’s ample market for a drug that mimics its benefits.

“There’s clearly a need to develop alternatives for relief of acute and chronic pain that go beyond opioids,” says Akhtar.

“These molecules are non-psychoactive and they target the inflammation at the source, making them ideal painkillers.” 

This research has been published in Phytochemistry.

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Is The Death Of Your Dream, A Reawakening?

 

Pink Sky Moonrise Over Florida   December 2019         ALL RIGHTS RESERVED

This past year has been filled with a full range of emotions. January 1, 2019. From the beginning of this year, the date of the death of my aunt,  became the catalyst for my traveling to California and from there began an adventurous ride that continues to today. During this year I have encountered many new and exciting precepts of my upcoming journey. As I reflect on this amazing pathway that I have chosen to be my roadmap to my future, I must first make state that as I am referencing myself in this writing, I cannot fully impress on, those reading this, of how my wife, Janet, has been the impetus of all my motivation and the drive for the direction my company is moving. I give all the glory to God and pray for divine interpretation. Meanwhile,  I have been taking time during the past few weeks to focus on the upcoming year 2020. My usual  attempts to plan anything have been thrown out the window. I am reinventing my goal setting, reworking my flowcharts and diagrams with the newfound knowledge and true inspiration that I have been soaking up these past 350 days. My newfound peer group is now made up of a multi-talented group of self motivated individuals, who I have drawn my courage from and fearlessness to  jump into the preverbal fire. At the end of this year, I encountered another death. This one was a catastrophic nightmare, in not only my mind, but also my company’s growth. However, I have woken up and now realize the opportunities afforded me during my sleep. Now, it is eyes wide open and the exuberance of the new days ahead. I am eternally grateful for the direction my mentors have provided me. 2020 is going to be the year of positive changes for those who live an awakened positive life.

Steven M Smith

CEO FOUNDER INSPIRATIONAL TECHNOLOGIES 2019

Inspirational Technologies is a Company Founded on the Ideals of Inspiring Collective Minds to Foster Health, Wellness and Compassion in our Human Interest of Peace, Love and Tolerance of each other’s human condition. We, the Company, strive to deliver to our consumers inspirational and insightful informational topics relevant to our mission. 

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