Posted on 11/21/2025 by Steven M Smith — Leave a comment

CBD Pain Relief Capsules and Predictive AI: How Innovation Is Shaping Wellness Solutions

Introduction: The CBD Wellness Revolution Meets Predictive AI

The intersection of CBD (cannabidiol) science and predictive artificial intelligence is sparking a new era in wellness product development. As pain management remains a top concern for billions worldwide, CBD capsules have risen in popularity—heralded for their potential analgesic and anti-inflammatory benefits, ease of use, and precise dosing. But what sets apart the fastest-growing brands in an increasingly crowded market is their embrace of AI-driven innovation, from ingredient optimization and supply chain management to hyper-targeted consumer engagement and next-generation product launches.

This blog, prepared for the PaiNT Network’s PaiNT Research Initiative and Implementation, distills essential findings from deep research into the CBD pain relief capsule landscape and explores the transformative power of predictive AI in wellness. We’ll cover ingredient differentiation, clinical efficacy data, consumer sentiment, AI modeling techniques, emerging market and regulatory trends, as well as real-world examples, so you can grasp the current state and compelling future of AI-augmented wellness product innovation.

Ingredient Differentiation: Precise Formulation as a Market Differentiator

Modern CBD pain relief capsules reflect a new sophistication in formulating for bioavailability, efficacy, and consumer experience. While CBD remains the central active ingredient, product differentiation increasingly hinges on the type of CBD used—CBD isolate, broad-spectrum, and full-spectrum—each with unique cannabinoid, terpene, and flavonoid profiles.

CBD Isolate Capsules: Pure CBD with no detectable THC or additional cannabinoids. They appeal to users seeking to avoid THC and are often preferred for regulatory compliance and precise therapeutic targeting.
Broad-Spectrum Capsules: Featuring CBD plus minor cannabinoids and terpenes, but with THC removed. These formulas aim to harness the “entourage effect” without THC’s regulatory or psychoactive baggage.
Full-Spectrum Capsules: Contain CBD along with all naturally occurring hemp plant components, including up to 0.3% THC. Full-spectrum capsules are associated with enhanced analgesic and anti-inflammatory benefits, attributed to synergistic plant compounds.

The most innovative capsules go further, integrating functional botanicals and adaptogens (like turmeric, ginger, or ashwagandha), advanced encapsulation (e.g., liposomal or nanoemulsion technology for superior absorption), and premium excipients geared for taste masking, vegan compliance, and allergen avoidance.

“Smart” ingredient stacking is a hallmark of leading brands. For example, some capsules targeting pain management blend full-spectrum CBD with curcumin—boosting anti-inflammatory action—while others employ melatonin or valerian for sleep/pain dual-action products. Innovations like Imuneks Farma’s “CBDNEXT Supra” solid capsules have demonstrated dramatically improved bioavailability, leveraging surfactant-rich, micro-emulsifying excipient blends.

Ingredient transparency and third-party testing (for purity, potency, and absence of residual solvents or contaminants) are increasingly considered non-negotiable by both the market and better-informed consumers.

Clinical Efficacy and Safety: What the Science and Studies Say

Pre-Clinical Insights

Pre-clinical research provides convincing evidence for CBD’s anti-inflammatory and analgesic properties, showing it acts on multiple receptors and pathways: TRPV1, serotonin receptors, and especially the endocannabinoid system (CB1, CB2). Animal studies confirm that both isolated and spectrum CBD formulations reduce markers of inflammation, diminish joint/muscle pain, and improve mobility in various pain models—hoisting CBD as a scientifically promising multitarget agent.

Clinical Evidence to Date

Clinical trial data is nuanced but promising:

Surveys show over 60% of CBD users utilize it for pain relief, with arthritis, musculoskeletal pain, and chronic pain being major targets. Many users report that CBD “works very well by itself”.
At least five published clinical trials report improvement in pain with oral CBD; topical CBD has more consistent support, particularly for arthritis.
A 2024 randomized crossover study found that advanced capsule formulations (like CBDNEXT Supra) achieved 5-6x higher peak CBD blood concentrations compared to plain, unformulated capsules—offering a pharmacokinetic advantage likely to boost real-world efficacy.
Patient reviews highlight real-world effectiveness, especially for those with fibromyalgia, joint pain, or sleep-pain comorbidities, and highlight notable reductions in prescription medication needs for some individuals.

Safety: Side effects are generally mild (sleepiness, mood changes, GI disturbances, appetite alterations). Yet, high-dose or chronic use (especially alongside other medications) demands liver monitoring, as recent FDA trials indicated elevated liver enzymes in a small subset of users.

Knowledge Gaps

Despite strong anecdotal and preclinical evidence, human trials often yield mixed results—sometimes due to low dosing, poor formulation, or variable study design. Consensus is forming that effective pain relief likely depends on advanced formulations, higher dosing, and possibly the inclusion of additional cannabinoids and terpenes (entourage effect). Ongoing studies (over 30+ trials in chronic and acute pain) are expected to provide greater clarity in the next several years.

Consumer Sentiment: Trust, Experience, and Expectations

Quantitative Sentiment

Over 60% of users aged 26–76 cite pain relief as their main reason for using CBD—making it the second most popular motivation after anxiety/mental wellness.
Ratings on platforms like WebMD and Medical News Today average 4.0/5 for pain and satisfaction, with highest praise for improved mobility, muscle relaxation, and fewer side effects compared to opioids or NSAIDs.

Qualitative Insight

Real-world testimonials reinforce the preference for capsules as a precise, flavorless, and portable delivery format. Users consistently praise the convenience, predictability of effect, and discreetness compared to oils, tinctures, and edibles. Negative reviews often cite variability in onset time, inconsistent product quality, and rare adverse effects like sedation or mood changes.

Emerging Themes:

“Nanoemulsion” and “liposomal” capsules are increasingly noticed for faster and stronger absorption—“competitively on par with prescription medication efficacy, without sedating side effects.”
Consumer trust hinges strongly on third-party lab results, batch traceability, and brand transparency regarding ingredient sourcing and testing.
Personalized dosage recommendations, responsive customer service (often delivered by AI chatbots), and educational resources are emerging as critical elements for brand loyalty.

Predictive AI in Wellness Product Development: The Engine Behind Next-Gen CBD Capsules

Predictive Modeling: From Formulation to Market

Machine learning (ML) and AI-driven predictive analytics are supercharging every dimension of the CBD capsule R&D and commercialization pipeline:

Formulation Optimization: AI algorithms model complex ingredient interactions, stability, and bioavailability, predicting which combinations and excipient profiles will maximize efficacy and minimize cost. Recent research shows ML-driven solid lipid nanoparticle (SLN) and nanostructured lipid carrier (NLC) optimization can increase CBD solubility/bioavailability up to 3000-fold in vitro, enabling rapid virtual screening and experimental validation.
Bioavailability Prediction: AI models predict in vivo pharmacokinetics based on excipient mix, capsule coating, and user characteristics, facilitating the leap from animal to human outcomes.
Consumer Sentiment Analysis: Natural language processing (NLP) tools mine consumer reviews, social signals, and market trends, surfacing gaps, opportunities, and optimal messaging for new formulations.
Behavioral and Cluster Analysis: Advanced clustering, journey mapping, and real-time segmentation enable brands to tailor products and marketing to micro-demographics, improving launch ROI and building true personalization into product pipelines.

Table: Key Outcomes of AI Integration in the CBD Capsule Sector

Process Area	AI Impact/Outcome
Product Development	65–70% of companies use AI; development cycles -35%
Bioavailability/PK Predictive Models	Virtual design to optimize nanocarrier composition
Personalized Product Recommendations	60%+ companies exploring, boosting engagement
Sentiment Analysis	55% use AI tools; improves product/brand alignment
Supply Chain Optimization	45–80% apply AI tools; error/recall rate -22%
Regulatory and Compliance Monitoring	62–77% rely on AI to track changing laws
Marketing & Targeting Automation	64–72% automate digital ad spend, +40% sales lift
Customer Service Chatbots	Boost satisfaction by 35%, response times -45%
Product Recall Management	AI-driven traceability enables targeted recall

Analysis: The widespread embrace of AI, from R&D to CX and compliance, is a primary factor differentiating fastest-growing brands and improving both operational efficiency and consumer outcomes.

Market Trends and Regulatory Landscape

Market Growth & Consumer Trends

The global CBD capsules and softgels market is set to reach $2.5–7 billion by 2033, growing at 15–23% annually. North America and Europe lead in adoption and regulatory clarity, with Gen Z and millennials driving demand for natural, plant-based, and sustainable wellness options.
Capsules and softgels are rapidly outpacing tinctures and topicals due to convenience, standardized dosing, and palatability. The “entourage effect” remains a selling point for full- and broad-spectrum products.
Online/direct-to-consumer channels dominate distribution, buoyed by digital marketing and AI-driven product recommendation systems.

Regulatory Picture

While the U.S. allows hemp-derived CBD capsules with ≤0.3% THC, the FDA prohibits marketing CBD as a food or dietary supplement and restricts disease claims, pending new Congressional pathways.
Europe is moving toward harmonization, but country-level restrictions persist, especially around novel food status and allowable claims.
Key compliance trends: third-party testing, transparent supply chains (bolstered by blockchain tech), and eco-friendly packaging are crucial for market access and consumer trust.

AI in Action: Real-World Examples and Case Studies

1. Automated Formulation & Clinical Success

Imuneks Farma’s “CBDNEXT Supra” capsule, designed with a proprietary, AI-informed mix of surfactants, acids, and polysaccharides, achieved a 5.6-fold increase in bioavailability over traditional CBD isolates in controlled clinical trials. Such tech-augmented formulation represents the near future for pain relief capsules—allowing lower doses, faster onset, and more predictable clinical effect.

2. Personalized Product Matching and Auto-Segmentation

AI-powered platforms now analyze biomarker and behavior data to offer personalized capsule recommendations, dynamically adapting suggestions to evolving health states and preferences. Companies using such systems see higher conversion rates, improved outcomes, and greater customer satisfaction.

3. Predictive Analytics in Customer Engagement

One Canadian CBD brand, using AI-generated personalized video messaging, drove a 150x ROI in customer retention campaigns, alongside a >70% email open rate—demonstrating the impact of predictive marketing and tailored engagement, especially under digital ad restrictions.

4. Supply Chain, Traceability, and Compliance

Blockchain-based AI traceability systems now enable transparent sourcing, batch-level tracking, and rapid recall if needed. QMS (Quality Management Systems) tools further automate compliance, optimizing logistics and regulatory documentation for global operations.

Capsule Formulation and Delivery: The Technology Edge

Emerging technologies are reshaping capsule efficacy and reliability:

Nanoemulsion and liposomal delivery platforms are at the forefront, transforming hydrophobic CBD into more water-compatible, cell-permeable micro-droplets that dramatically improve absorption and onset speed—sometimes reducing the “wait for relief” from 1–2 hours (standard) to as little as 15–30 minutes.
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC), designed and optimized with AI, now deliver consistent, improved bioavailability and protection against digestive degradation.
Sustainability and clean label sourcing (plant-based or pullulan capsules, minimal excipient load, biodegradable packaging) are now expected by savvy consumers and major retailers.

Safety Considerations and Side Effect Management

Most CBD capsules, when used as directed, are well-tolerated. However, recent FDA and clinical data indicate potential liver enzyme elevation in a small percentage of users, especially at moderate to high daily doses or alongside other medications.
Other common effects: sleepiness, mild GI issues, rare mood changes.
Risks are greater for vulnerable populations (pregnant/breastfeeding women, those with liver disease, or complex medication regimens), underscoring the need for physician guidance and well-labeled products.
Product purity remains a concern: up to 30% of OTC CBD products are inaccurately labeled, sometimes containing unexpected levels of THC or contaminants. AI-enhanced quality testing and batch-level transparency are elevating industry standards.

The Future: Convergence of AI and CBD for Precision Wellness

Looking ahead, the convergence of AI and CBD innovation is geared toward precision wellness—delivering right-fit products to individual consumers at the right time, optimizing both health outcomes and business growth.

Predictive analytics will continue to expand in product design, demand forecasting, and even clinical outcomes, allowing earlier, more accurate pain management interventions.
Personalized journeys will enable dynamic dosage recommendations, side effect monitoring, and outcome tracking.
The supply chain—and thus, quality control—will become increasingly automated, transparent, and resilient.
As regulation catches up, brands that prioritize data integrity, responsible AI, and science-backed formulation will set the industry standard.

Conclusion: Strategic Takeaways for Industry and Innovators

CBD pain relief capsules represent one of the most promising frontiers in natural pain management. As consumers demand proven efficacy, rigorous safety, sustainability, and meaningful personalization, product leaders must harness both cutting-edge formulation science and the predictive power of AI.

For companies and R&D teams in the PaiNT Network and beyond, the blueprint is clear:

Invest in AI-driven formulation and data-backed innovation to differentiate in a saturated market.
Prioritize robust clinical validation and transparent safety reporting, especially around bioavailability and tolerability.
Leverage AI across the product lifecycle: from market sensing and sentiment analysis to agile supply chain and quality compliance.
Engage with evolving regulatory frameworks proactively, using digital traceability and blockchain for trust.
Commit to continuous feedback loops—capturing data from every capsule consumed and adjusting swiftly to consumer and clinical insights.

Steven Smith Notes: “The convergence of predictive AI and advanced CBD science is more than a trend—it’s the path to a new paradigm in wellness, rooted in precision, transparency, and consumer empowerment. The brands and innovators who seize this opportunity are poised not just to lead, but to transform, the future of pain relief and holistic health.”

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We, at Inspirational Technologies are at the forefront of Inspirational and Frontrunners on the frontier of current technology.

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We hope this information has been helpful and informative. Don’t hesitate to reach out with any further questions. 😊

Predictive Artificial Intelligence News & Technology

Posted on 08/04/202408/05/2024 by Steven M Smith — Leave a comment

Can CBD Improve My Health and Wellness?

Oil, gummies and what you should know.

The global cannabidiol, or CBD, market is exploding, with analysts projecting it will hit 22.05 billion by the year 2030. That’s nearly 20% of the size of the global soft drinks market even though CBD was only legalized in the U.S. in 2018 while the soda market has existed here for nearly 200 years.

In a few short years, CBD products have sprouted up everywhere and are available for purchase in the form of oils absorbed on one’s tongue, edibles such as gummies, candies, foods, pills or beverages, topical applications of ointments, creams or lotions absorbed on one’s skin, and inhalation by vaping or smoking.

What is CBD?

CBD is a chemical compound largely derived from hemp in the cannabis (marijuana) sativa plant. The plant has over 85 chemicals that are identified as cannabinoids, but cannabidiol is the most frequently used one for medical purposes due to its lack of psychoactive effect.

There are three main types of CBD:

full-spectrum CBD, which contains all beneficial compounds naturally found in the cannabis plant;
broad-spectrum CBD, which contains only some such compounds;
and CBD Isolate or “pure CBD,” which doesn’t contain any delta-9-tetrahydrocannabinol, or THC, nor any other compound from the hemp plant.

Legally, no CBD products can contain more than 0.3% (by dry weight) of THC, the mind-altering substance in marijuana known for its psychoactive effects.

Because of this, “CBD is not intoxicating and will not make you high” as some people believe, explains Janice Newell Bissex, MS, RDN, FAND, holistic cannabis practitioner at Jannabis Wellness. Instead, “CBD interacts with our endocannabinoid system,” she says. One’s endocannabinoid system (ECS) is a widespread neuromodulatory system that “plays a role in regulating pain, mood, immune function and inflammation,” says Josh Redd, NMD, the founder of RedRiver Health and Wellness and author of “The Truth About Low Thyroid.”

What does CBD do?

In this interaction with one’s endocannabinoid system, the chemical compound works to calm one’s nervous system, reduce inflammation and alleviate some chronic pain symptoms. Harvard Medical School says “there is moderate evidence that CBD can improve sleep disorders, fibromyalgia pain, muscle spasticity related to multiple sclerosis and anxiety.”

Bissex adds that some people find that CBD can also be a helpful treatment for traumatic brain injuries or seizures. Redd says the chemical compound has properties that can alleviate some epilepsy symptoms and provide autoimmune management as well.

Is CBD considered a drug?

Though CBD does affect the structure or function of the body, as the Food and Drug Administration (FDA) defines a drug, CBD is not classified as a narcotic drug. The Centers for Disease Control and Prevention (CDC) notes that CBD is not impairing, and the World Health Organization‘s Commision in Narcotic Drugs found that the chemical “has no potential for abuse and no potential to produce dependence.” Bissex adds that CBD has a good safety profile and is “generally well tolerated.”

Redd agrees that the chemical is well received by most users but says we still “lack long-term studies.” He adds that “the biggest concern with CBD is that the market is not fully regulated, and the quality and purity of CBD products can vary.” The CDC similarly notes a lack of regulation and says that because scientists are still learning about how CBD affects the body, it strongly suggests keeping CBD products “in childproof containers and out of the reach of children.”

The agency also warns adult users of potential harms and side effects associated with taking CBD products. These include liver damage, upset stomach, changes in one’s appetite, irritability and interference with other drugs one is taking that may cause more serious problems. Bissex says other side effects of using CBD products may also include “vivid dreams, fatigue and low blood pressure.”

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I hope this information was helpful and informative. If you have any more questions, please feel free to ask me. 😊

Inspirational Technologies – IT is Time

We, at Inspirational Technologies are at the forefront of Inspirational and Frontrunners on the frontier of current technology.

We are often faced with our own personal conflicts which directly influence our interactions with our peers and family.

When Inspirational Technologies is an endorsement of the “Cannabis” approach to the medical condition, we say, let’s let the look at the data and the people who say that they benefit for cannabis alternatives.

Steven M Smith InspirationalTech.org CEO since 2013.

Thank you for consideration.

Inspirational Technologies

Posted on 08/03/202408/03/2024 by Steven M Smith — Leave a comment

What Is CBD & How Does it Work?

CBD has been taking the health and wellness industries by storm. From oils and tinctures to gummies and lotions, the numerous varieties of CBD products available today are remarkable. The incremental growth of the CBD oil market alone is estimated to be $3.52 billion between 2019 and 2024. But what actually is CBD and how does it work? Read on for a beginner’s breakdown to what CBD is, why it works in the human body and who can use CBD for what.

What is CBD?

Cannabidiol, often abbreviated to CBD, is a naturally occurring compound found in the Cannabis sativa plants, hemp and cannabis. Manufacturers extract and process the CBD to isolate it for various uses; besides the oils, there are edibles and topicals.

How is CBD different from THC?

THC, or tetrahydro-cannabidiol, is the main psychoactive component in the cannabis plant that creates a “high” sensation. THC is primarily consumed through inhalation of smoke or through edibles, oils or capsules. Both THC and CBD interact with bodily systems, but according to research, THC interacts primarily with CB1 receptors which are linked to the high or euphoric feeling. Hemp plants contain a higher percentage of CBD while maintaining very low levels of THC.

How Does CBD Work in the Body?

CBD works directly with the human body’s endocannabinoid system, or ECS. CBD intercepts both the CB1 and CB2 receptors in the ESC, which are primarily responsible for transmitting messages to the brain. The ECS regulates a broad spectrum of biological and physiological processes including pain management, inflammation, sleep, mood, digestion and more.

What Are the Health Benefits?

The health benefits of CBD are being recognized. In June 2018, the FDA approved the first prescription medication containing CBD, Epidiolex. It is used to treat rare and difficult-to-control forms of epilepsy. Because CBD regulates receptors, researchers hope that early research showing promise for certain autoimmune diseases will show the same results in humans. Proprietary research indicates CBD could help:

-inflammation

-chronic pain

-anxiety

-depression

Though CBD is rapidly gaining in popularity, there are more clinical trials and studies needed to confirm its full impact and effectiveness. There has been some evidence of side effects accompanying CBD, but if you are a first time user consulting your doctor, or a medical professional is always a good place to start.

Is CBD Legal?

December 2018 – The Farm Bill Legalized Hemp

Cannabis- and hemp-related laws in the United States are evolving and changing rapidly. Hemp, when produced at levels below 0.3% delta-9 THC, is not considered a controlled substance at the federal level. Hemp-derived CBD is accessible in most of the 50 states. A Drug Enforcement Administration registration is not required to grow or research it.

Industrial hemp, given in its legal definition in the 2018 Farm Bill, is legitimate if companies are transparent in their manufacturing process and label claims. But each state has its own laws and regulations, so check with your state’s protocols before purchasing CBD.

CBD Takeaways

The hype surrounding CBD is real and does seem relevant. Though there is still more research needed surrounding the impact and potential side effects of CBD, anecdotal evidence and early-stage studies have shed some positive light. If you are curious about using CBD and aren’t sure where to start, begin with a reliable source. Always turn to third-party lab test results to ensure the quality, potency and purity of your CBD product. Choose independent companies with labs like Real Tested CBD to explore which CBD products have tested accurately to label claims and serve best for you.

CBD seems to be popping up everywhere claiming to cure every illness under the sun, but does it really work and if so how? Sometimes it can feel like a modern version of the snake oil salesman and I must admit I was skeptical. After many recommendations from friends and a big interest from my community, I decided to give it a try and I am excited to share my experience after 8 weeks of consistent use

What Is CBD & How Does it Work?

CBD (short for Cannabidiol) is one of more than a hundred phytocannabinoids, which is unique to cannabis and provides benefits to the body through the endocannabinoid system. Cannabinoids are chemical compounds that interact with your biological processes to produce a desired effect.

So how does CBD work in your body? Your Endocannabinoid System (ECS) works to balance all your body’s functions and the phytocannabinoid CBD can help to replenish deficiencies due to stress and inflammation. Learn more about CBD Basics

A common misconception is that taking CBD can lead to being “high”. Hemp derived CBD products only contain trace amount of THC, which help amplify the therapeutic benefits.

Want to learn more about CBD? Check out this article from the WHO showing that CBD is non-habit forming and safe for consumption.

This article from Project CBD also provides a great science background on CBD.

How to Choose a High-Quality CBD

Just like the food you eat, CBD quality is key! I highly suggest you do your research and talk to your doctor before taking any supplement.

When looking for high-quality CBD you want to ensure the product is third-party lab tested, to ensure it is free from heavy metals and harmful pesticides and you want a full spectrum CBD with a tiny amount of THC, which makes it more effective.

What Did I Hope to Gain with CBD?

I started taking the CBD in mid-May and like many of you my anxiety had been at an all-time high. While I am on low-dose anxiety medication and have been for many years, I was excited to see if the CBD could help regulate my moods. I knew very well that CBD could not eliminate my anxiety, but I was curious to see if it could help with the peaks and valleys of tension and stress that at the time were consuming me daily!

My CBD Dosing

Keep in mind that your dosage will be customized to your body, and your needs and can take up to 3 months to see the full effects. It took me about 2 weeks to find a good routine/dose that worked best for me.

8:30am: 1 – 25mg full spectrum soft gel with my coffee. The gel is a slow release and meant to slowly balance you throughout the day. * I started on the 10mg and worked up to the 25mg

Side Note: They did suggest taking the capsules with a fatty food for better absorption, which I was doing until I recently switch back to intermittent fasting.

5:00pm – 1/2 dropper (5mg/0.5ml) Daily Drops, pre witching hour, or as needed to manage peaks and valleys of stress. I find the time when I transition from my day job to #momlife + blog life can be most stressful

Bedtime: 3/4 dropper (7mg/0.75ml) daily Drops before bed split into two doses to more easily absorb under my tongue. Letting it absorb vs. swallowing right away helps it absorb into your bloodstream quicker AND it tastes a little less gross. Cannabis has a distinct taste that reminds me of a medicinal herb, but it’s nothing awful.

Episodic Dose: You can also use your drops episodically as needed. So, if I find myself feeling particularly overwhelmed or anxious, or I know I’m headed into a stressful situation, I will do a 1/2 dropper (5mg/0.5ml) of the Daily Drops.

Science Tip: The drops under the tongue are absorbed and take effect faster but are quicker to leave your body so that is why they work for episodic stress. The capsules on the other hand have a slower onset but have a lasting effect throughout the day.

Did CBD Work for Me?

YES! Despite my skepticism, the consistent addition of CBD to my routine has made a big difference in both my anxiety levels and how quickly I am able to wind down for bed at night.

In order to share more than just my anecdotal experience, I decided to track my stress factors for the first 7 days of my CBD experience.

Stress manifests for me as:

So many to-do lists/post-its
Uncontrolled screen-time
Throwing myself into work (particularly the blog)
Excessive multi-tasking
Racing heart rate

Here are my results for the first 7 days of CBD use

Day 1: 5/5 predictors present
Day 2: 5/5 predictors present
Day 3: 4/5 predictors present
Day 4: 1/5 predictors present
Day 5: 0/5 predictors present
Day 6: 0/5 predictors present
Day 7: 0/5 predictors present

Do I still have rough days? Absolutely! But the way I know the CBD is working is that if I miss a day, I immediately notice I am more irritable, more controlled by my anxiety and quicker to snap at family and friends. It’s such a gradual balancing that leaves me feeling like the best version of myself!

Each person’s experience will be unique. Like any supplement you should consult with your doctor before use and keep in mind that results may take up to 3 months to be evident.

We, at Inspirational Technologies are at the forefront of Inspirational and Frontrunners on the frontier of current technology.

We are often faced with our own personal conflicts which directly influence our interactions with our peers and family.

Everyone is trying to get better sleep today, and there is no shortage of products that promise to help ease you into deeper slumber, from weighted blankets to fancy sound machines. But more and more people are adding CBD to their sleep checklist as well.

“I used to have trouble with sleep,” Barker tells Rolling Stone, “And I would take a ton of melatonin, valerian tea, Tylenol PM, or Nyquil,” he admits, “but CBD was like the best kind of result that I got.”

The immediate benefits that Barker found with CBD led him to create Barker Wellness, a new line of cannabinoid-infused products that includes a unique CBD tincture for sleep. While CBD is not a medically approved solution for sleep, experts say a little CBD could go a long towards promoting more soothing, stress-free slumber.

How Does CBD Work for Sleep?

“CBD is a compound that supports a powerful, yet widespread network of receptors in the body called the endocannabinoid system (ECS), which is known to help regulate energy, mood, sleep, and more,” explains Dr. Jason Wersland, Founder and Chief Wellness Officer of Therabody, the newly rebranded company that now includes the popular Theragun percussion devices. “Researchers have found that CBD, found naturally in the hemp plant, interacts with ECS receptors throughout the body much like molecules the body naturally produces.”

Experts say the best CBD products for sleep also help you wind down by addressing some of the root causes of restlessness and stress.

“Most people don’t realize the quality of sleep is closely related to stress and maintaining a strong immune system, and you need both systems properly in check if you want an optimal immune response to anything,” adds Jay Hartenbach, CEO of CBD brand Medterra. “If your cortisol levels are elevated, it can keep you awake. CBD is thought to decrease this and keep your body in a homeostasis state.”

If you’re just easing into CBD, Hartenbach suggests finding CBD products that also contain other ingredients that work together to help you feel more restful and relaxed. “CBD, amino acids, L-theanine and 5-HTP, and relaxing herbs like passion flower, chamomile, and lemon balm have each individually been shown to help with providing a full restful night and have been expertly formulated to work together for desired results to address the most common issues,” Hartenbach says. “Proper sleep and circadian control are absolutely essential to an optimally functioning immune system. If your body lacks restful sleep, so does your immunity.”

Will CBD for Sleep Make You Drowsy or High?

The best CBD for sleep is designed to help you ease into slumber – not knock you out. And unlike THC, which may have some psychoactive effects, Wersland says “CBD is non-intoxicating and will not make you feel high.”

If you’re new to CBD, trying a CBD gummy for sleep is an easy way to test out its effects in an easy-to-take format (basically like a gummy bear or gummy vitamin). Many brands also have flavorless CBD oils (or “CBD tinctures”), which come out of a dropper, letting you control exactly how much you want to take. Wersland’s suggestion: start small and then see how the tincture affects you. “If you’d like to take one full dropper that’s 33mg of full-spectrum CBD you can,” he says, “or you can take a ¼ of a dropper which is about 8mg of CBD.”

Of course, CBD is primarily meant for therapeutic benefits and is not meant to replace any doctor-recommended prescriptions if you suffer from serious insomnia. You should also see a doctor if you have a severe sleep disorder, restlessness or anxiety, as CBD is not meant to treat those issues.

A recent clinical trial has identified potential therapeutic benefits of cannabigerol (CBG), a cannabinoid that has not been as widely studied as THC or CBD.

The study, conducted by researchers at Washington State University (WSU) and the University of California, Los Angeles (UCLA), indicates that CBG may significantly reduce anxiety and stress, and could also improve memory.

Published in the journal Scientific Reports, the research involved a double-blind, placebo-controlled field trial with 34 healthy adults.

Participants received either 20mg of hemp-derived CBG or a placebo tincture over two sessions. They completed online assessments before and after taking the cannabinoid, including surveys on anxiety and stress, as well as verbal memory tests.

The study found that CBG led to “significant overall reductions in anxiety as well as reductions in stress” compared to the placebo. Additionally, participants who took CBG showed enhanced verbal memory, which the researchers noted was “completely, entirely unexpected.”

“The finding that it significantly enhanced [memory] was kind of shocking to me and completely, entirely unexpected, which was why I triple-checked the direction and the result,” Cuttler added.

Future Research Directions: What’s Next for CBG?

Cuttler stressed that while the results are promising, further research is needed to confirm these findings and explore CBG’s full range of effects. “Replication and further research are crucial,” she said.

The trial’s results were informed by a prior survey in which 51% of CBG users reported using CBG to alleviate anxiety, with nearly 80% finding it more effective than traditional anxiety medications.

Cuttler is seeking approval for a follow-up clinical trial to be conducted in a laboratory setting to verify these findings and assess CBG’s physiological impacts. She is also exploring potential research on CBG’s effects on menopause symptoms.

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I hope this information was helpful and informative. If you have any more questions, please feel free to ask me. 😊

Inspirational Technologies – IT is Time

We, at Inspirational Technologies are at the forefront of Inspirational and Frontrunners on the frontier of current technology.

We are often faced with our own personal conflicts which directly influence our interactions with our peers and family.

Steven M Smith InspirationalTech.org CEO since 2013.

Thank you for consideration.

Inspirational Technologies

Posted on 12/27/202212/27/2022 by Steven M Smith — Leave a comment

What is CO2 Extraction? What Hemp and Marijuana Growers Need to Know.

What is CO2 Extraction? The Supercritical CO2 extraction process creates phase changes in carbon dioxide utilizing temperature and pressure.

CO2 is known as a “tunable solvent” making it extremely versatile for creating a multitude of end products by controlling temperature and pressure.

These phase changes create an environment to drop out differing weights of components in the plant material.

The unique design of the Hi-Flo™ Series systems allow for separation and collection of these constituents during a single extraction.

This enables collection of light essential oils separately from other desirable constituents and heavier lipids.

Supercritical CO2 fluid extraction (SCFE) methodology delivers a clean, unaltered, consistent-yet-flexible product.

Removable Molecular Components is a Positive Clean Alternative for CBD Extraction

CO2: Clean, Safe, Quick CO2 Extraction is good business.

It allows you to create a pure, clean, quality oil that is safe to produce with little-to-no post-processing.

Processes that use toxic solvents may require many hours to purge the solvent trapped in the oil.

Multiple industries have proven that the highest efficiencies in commercial processing utilize CO2. CO2 offers you the ability to “tune” the extraction process, especially with a system that will separate constituents during an extraction.

You can target specific compounds, like terpenes (terpenoids) and THC/CBD (cannabinoids) through different operational parameters.

CO2 is also a sanitizing agent, prolonging shelf life, and, with t

he proper system and environment, yields food and medical grade oils.

CO2 extraction is a safe, clean, and highly versatile method of extracting plant botanicals, nutraceuticals, hops, and hemp.

For the Originality in Extraction

Supercritical carbon dioxide (sCO₂) is the most widely used fluid for the Supercritical Fluid Extraction (SCFE) process across the globe. Not only is sCO₂ capable of extracting the required ingredients in their pristine form, the prime reason for the surging popularity of SCFE, it also makes the process more manageable, economical, and safe.

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Buffalo Extraction Systems Carbon dioxide (CO₂) Supercritical Fluid Extraction (SCFE) Plant

These days, “clean label” products are selling like hot cakes. Increasingly health-conscious customers are placing a premium on natural ingredients in the food, pharmaceutical, beverage, and neutraceutical products they consume. Now, clean label is a broad term with various meanings – organic, natural, locally grown, non-GMO . . . the list goes on. Some even take it to link its maker to more transparent work practices.

Alternative processes such as Solvent Extraction and Hydro distillation leave behind harmful residues. Plus, they distort the ingredient being extracted. That is, the ingredient does not retain its natural purity. Regulations have caught up with public demand and impose exacting conditions to ensure the quality and safety of products by limiting toxic residues. One more reason to rely on CO₂ SCFE.

What Makes Supercritical Carbon dioxide (sCO₂) an Exceptional SCFE Solvent?

Carbon dioxide and water are the most widely employed supercritical fluids. sCO₂ makes such a useful supercritical fluid because:

Has a critical temperature of 31.10C, which is around the ambient temperature improving its compatibility with temperature-sensitive compounds.
Has a more manageable critical pressure of 73.9 bar.
Is non-flammable and non-toxic.
Has a customizable density to upgrade its solvent power.
Is available in ample quantities and in pure form; and
Has a comparatively low cost.

Although CO₂ is a greenhouse gas (GHG), the SCFE process using CO₂ becomes eco-friendly if the gas is captured from the atmosphere and recycled.

Carbon dioxide Supercritical Fluid Extraction (CO₂ SCFE)

Solvent Extraction employs organic solvents to dissolve the ingredient from the raw material. Later, it separates the organic solvent from the dissolved ingredient. The problem is, organic solvents do not completely disassociate from the ingredient, leaving behind residues.

Parameter	Solvent Extraction	SCF Extraction
Solvent traces in final product	Yes	Zero
Heavy metal content in final product	Yes	Zero
Inorganic salt content in final product	Yes	Zero
Similarity with the actual components to be extracted in terms of Colour and Flow Characteristics	Less: because polar compounds get dissolved.	More: because low operating temperatures and selective extraction of CO₂.

Table 1. SCFE Vs Solvent Extraction

That is, the ingredient loses its natural purity. What is more, it may develop a certain degree of toxicity. But the concerns on using organic solvents for extraction go beyond toxicity for the individual. Some solvents are ozone depleting substances, and their use negatively impacts the environment.

Hydro distillation i.e., the use of water and steam distillation inherently employs heat, something that thermally degrades the ingredients. Again, the ingredient, when extracted, is no longer available in its pure form.

Parameter	Steam Distillation	SCF Extraction
Extraction of essential, non-volatile oils	Not possible	Possible
Extraction of highly volatile oils	Not possible	Possible
Oxidation and Hydrolysis (undesirable)	Possible	Not possible
Similarity of essential oils with the extracted component in terms of Form, Aroma, and Physical Characteristics	Less	More

Table 2. SCFE Vs Steam Distillation

As a process that holds the United States FDA’s “Green Technology” approval, CO₂ SCFE enjoys sizable international clout. One reason for its eco-friendly nature is that it does not generate effluents, automatically eliminating pollution control hassles and costs.

Examined in the context of the limitations of hydrodistillation and solvent extraction, CO₂ SCFE delivers a much better performance on all fronts during the extraction of:

Plant-based Ingredients: Solvent extraction oxidizes the ingredient that lends color and aroma. Similarly, steam distillation acts strongly and ends up altering the component’s aroma. SCFE acts mildly, thereby avoiding such unwanted changes while also delivering cleaner, fresher, and crispier extracts.
Herbal Medicines: CO₂ SCFE is preferred over hydrodistillation when extracting essential oils because it does not thermally degenerate the oil. It is also replacing solvent extraction for seed oil separation as the solvent cannot be completely disassociated from the seed oil.
Astaxanthin Extraction from Haematococcus pluviales: CO₂ SCFE gives superior results vis-à-vis solvent extraction that employs acetone and hexane. These solvents cannot tell between astaxanthin and the astaxanthin-lipid mixture, both of which occur inside Haematococcus pluviales. As a result, these solvents deliver a low-concentrate extract.
Beer, Wine, and Blended Alcohol: CO₂ SCFE lowers the alcohol content of wine to a bare minimum while leaving its organopletic features undisturbed. The process also extracts the original versions of hop flavors while extending their life, thereby acting as a natural preservative for beer.

Organopletic properties of wines are their aroma, fruitiness, crispiness, sweetness, and freshness. Hop is the plant whose flower imparts the prized bitter taste to beer.

Phytochemicals: Because supercritical CO₂ is naturally nonpolar, it can better distinguish between volatile, non-polar, and low molecular weight phytochemicals [14].

The selectivity of SCFE is an asset here as it can separate anthocyanin from the pulp of Euterpe oleracea at a certain pressure while extracting phenolic phytochemicals from that very pulp at another pressure.

Algae:

Carotenoids: Hiking the pressure and temperature of the CO₂ SCFE process boosts the efficiency of carotenoid extraction. Utilizing the solvent extraction process for the same consumes large quantities of solvent, takes longer, and delivers impure and deficient yields.
Antioxidants: Employing CO₂ SCFE on Haematococcus pluvialis, a microalgae, gives good yields of lutein, astaxanthin, and fatty acids.
Fatty Acids: CO₂ SCFE is able to better differentiate between different fatty acids as compared to pyrolysis / thermal liquefaction and solvent extraction via hexane, the traditional methods for fatty acid extraction. Besides, these conventional techniques are slower.
Sterols: CO₂ SCFE enables solvent-free extraction of phytosterols that are safe for use in the food and beverages industries.

The Verdict

People the world over are shifting to natural alternatives – natural medicine, natural food, natural beverages – in realization to the long-term side effects that synthetic products, possibly laced with toxic residues, can unleash on health and overall wellbeing.

Effectively this means, the SCFE process and, more specifically, the CO₂ SCFE process, are here to stay . . . for ages.

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Our 4H Platform Uses HEMP as an Agricultural Focal Point, deserving of research, development and with the

4 Hemp key points being Health Hope and Happiness, thru Hemp“.

Cannabis CBD and Me

#AllRightsReserved-InspirationalTechnologies2022

Posted on 10/23/202211/30/2022 by Steven M Smith — Leave a comment

The Amount of Misinformation about CBD is ASTOUNDING! Gives Pause to the Real “Stuff”.

Over the past few years, CBD has taken the world by storm. Daily, I see claims that CBD “cures” a myriad of ills.

As a holistic nurse practitioner and certified herbalist for more than 30 years, those exaggerated claims “push my buttons”, for a variety of reasons.

How Do Cannabinoids Work?

We all have an Endocannabinoid System (ECS), and it is just as important as our Respiratory System, Cardiovascular System, or Immune System. The ECS is the “orchestra conductor” of the body.

It regulates multiple systems to achieve balance and harmony. The ECS operates behind the scenes to support the wisdom of every cell of the body and coordinate the functions of cells, tissues, glands and organs. (3, 4)

The ECS has three primary functions (2):

To balance hormones (sex hormones, thyroid hormones, stress hormones) for calm, relaxation, healthy metabolism & healthy stress response

To balance brain chemistry for optimal learning, focus, memory, concentration, mood, and restorative sleep

To support healthy cell function, including modulating inflammation and healthy immune response

Where Do Cannabinoids Come From?

Cannabinoids are not foreign to the human body. We manufacture them internally. (Endogenous cannabinoids are even found in human breast milk.) The issue is that our native cannabinoids are used up quickly when under physical or emotional stress. Supplemental plant-based cannabinoids attach to the same cell receptors in our bodies to support our innate ECS in performing its vital functions. They are a healthy insurance policy.

Several well-known plants contain cannabinoids. We automatically think of cannabis, since it is the richest source of these compounds. Both hemp and marijuana contain an assortment of cannabinoids, but marijuana is much higher in THC, the psychoactive molecule that makes you “high”. Hemp contains higher levels of CBD and other therapeutic compounds and extremely low levels of THC.

Additional plant sources of cannabinoids include well known plants like sunflowers, echinacea, black truffles, black pepper, and cacao.

You need to know that cannabidiol (CBD) is just one of approximately 400 therapeutic compounds found in the cannabis plant. CBD is extremely popular, but often misunderstood. The amount of misinformation about CBD is astounding!

Let’s take a look at the FACTS:

The cannabis family includes both hemp and marijuana. Marijuana contains a much higher percentage of THC, a psychoactive compound that can make you “high.” Depending on the variety, marijuana may contain anywhere from 5% to 30% THC. The average is about 12%.

By law, industrial hemp can only contain up to 0.3% THC (3 parts per 1,000). Hempsmart’s CBD based products are all derived from organically grown premium hemp.

CBD Isolate contains only the CBD molecule from the hemp plant. That single molecule is extracted from approximately 400 therapeutic compounds naturally found in hemp. It has some therapeutic effects, but only a small fraction of the entire plant’s potential benefits. Mother Nature has assembled a rich blend of synergistic plant compounds in the hemp plant. They are designed to function in harmony for a powerful “Entourage Effect.”

While some slick advertising claims that CBD Isolate is the “purest” form of CBD, that is because it is purely CBD, a single molecule, lacking the other synergistic plant compounds.

(1) This is the least expensive way to produce a CBD product. I compare it to purchasing a beautiful home with a great living room, but no kitchen or bath. It does not do a comprehensive job of meeting your daily needs.

Full Spectrum CBD (more accurately described as full spectrum hemp extract) contains all of the naturally occurring compounds found in the hemp plant. This full array of plant components works synergistically to support the ECS. The important Entourage Effect exists with full spectrum CBD. The downside is that full spectrum compounds contain the psychoactive component, THC.

It is true that THC has some beneficial effects, but some individuals should NOT use THC. Children, seniors, individuals with certain medical conditions, and those who are required to be drug tested, should avoid THC unless there is a specific indication for using that compound. Drug testing is designed to detect the breakdown products of THC, specifically. THC may also cloud mental acuity, even in small amounts. If you are looking for comprehensive support of your health, without the potential side effects of THC, then a premium quality broad spectrum hemp extract will best meet your needs.

Broad Spectrum CBD (more accurately, broad spectrum hemp extract) can provide the best of both worlds – the important benefit of the Entourage Effect without the potential problems sometimes associated with THC. The integrity of complementary cannabinoids, terpenes, flavonoids and other phytonutrients are included and provide the Entourage Effect. Broad Spectrum formulas generally omit the THC that can cloud mental acuity in some individuals and may also show up on a drug test.

NOTE: Every batch of every hempsmart product is verified, by an independent certified laboratory, to be THC-FREE. That means that there is no detectable level of THC. The integrity of other complimentary cannabinoids, terpenes, flavonoids, and other phytonutrients is maintained for the important Entourage Effect.

Safe and Effective CBD-based Formulas

There are some very good hemp-based products in the marketplace and many that are NOT worth your money. They certainly are not worth risking your health! Because there is little to no regulation on the quality of CBD formulas, it is important that you be a savvy consumer and make a well-informed decision. Do your homework right here and learn how to choose a legitimate non-toxic CBD formula that can support your health, without undesirable toxins and side effects.

Comprehensive Independent Lab Testing

In addition to knowing what IN your CBD products is, it is essential to know what NOT in them is! Hemp is good for the planet because it helps to clean the environment. It is quite effective at pulling toxins like pesticides and heavy metals from the soil. Any reputable hemp-based product should be validated by a comprehensive Certificate of Analysis (COA), from a certified independent laboratory. You should be able to see proof of testing for cannabinoid profile (including THC), terpenes, heavy metals, pesticides, bacteria, mold, and solvents. Every batch of every product should be tested, with the COA’s available for you to examine.

Beware of Exaggerated Claims:

You will see ads for CBD claiming to treat, prevent or “cure” a variety of illnesses or medical conditions. It is ILLEGAL to claim or imply that CBD treats or “cures” any disease (per decree of the FDA & FTC). it is also just not accurate! CBD does not treat or cure any diagnosis. What it does is much more powerful!

A premium quality broad spectrum CBD formula supports the wisdom of every cell of the body, thru the action of the ECS. It works at a foundational level to help maintain balance at a cellular level. A reputable, scientifically validated broad-spectrum hemp extract supports the ECS to function as a masterful “orchestra conductor” of the body so that balance and harmony is maintained between the cells, organs, gland and tissues. This is the foundation of wellness. (4)

The human body is designed to be resilient and resistant to health challenges. The best CBD based products are formulated with scientifically verified purity, potency, and integrity to support the healthy structure and function of your body and mind. Don’t buy “hype.” Invest in scientifically proven RESULTS.

Demand to see the Certificate of Analysis (COA) from an independent certified lab. That COA should include not just the cannabinoid and terpene content, but also the proof of a passing score on pesticides, heavy metals, bacteria, mold, foreign contamination and residual solvents.

At hempsmart, we are scientifically driven in our mission: Enhancing and Improving Lives.

We’re in this together.

Real results you can FEEL from the brand you can TRUST.

Resources:

https://www.projectcbd.org/science/pure-cbd-better

https://www.projectcbd.org/science/endocannabinoid-discovery-timeline

https://www.projectcbd.org/news/quick-hits/cbd-neurogenesis

https://www.projectcbd.org/wellness/endocannabinoid-system-biology-wellness-video

Inspirational Technologies 2022

InspirationalTech.org for your Health Wellness Beauty and Inspirational Goals

Inspirational Technologies – is Committed to Your Health Wellness Beauty and Enrichment

Reporting on Today’s Internal Botanical and Skin Product Benefits

4 Hemp Club was Inspired by Steven Smith’s vision to

“Have an older generation 4H Club, where an older community of adults could carry on what the younger 4H Club envisioned.

Our 4H Platform Uses HEMP as an Agricultural Focal Point, deserving of research, development and with the

4 Hemp key points being Health Hope and Happiness, thru Hemp“.

Cannabis CBD and Me

#AllRightsReserved-InspirationalTechnologies2022

Posted on 09/11/202211/19/2022 by Steven M Smith — Leave a comment

CBD Advertising, How Cannabis Legalization Has a Roadmap to Follow

It’s not every day that a product manages to grasp the attention of a global consumer market within such a short space of time.

However, cannabidiol – or “CBD” as most people call it – has contributed to a surge of enthusiasm in the medical market.

Perhaps one of the most frequently discussed cannabinoids, CBD controls an industry of its own and is on-track to harvest a generous $16.32 billion in the United States by 2026.

CBD Advertising, How Cannabis Legalization Has a Roadmap to Follow

Demand for effective CBD marketing is on the rise and there is no wonder why. So far, scientists have successfully isolated 113 of the leafy green plant’s active chemical compounds.

Formerly, the cannabis community firmly focused its attention on the plant’s psychoactive constituent TH-Cbd (tetrahydro-cannabinol) — but now, thanks to a swelling smorgasbord of scientific evidence pointing to the therapeutic potential of cannabis and hemp’s non-psychoactive chemical compound CBD, the market is constantly evolving.

CBD is enticing a diverse group of consumers from all ages — and even pets.