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President Joe Biden Announced Friday Intention To Nominate Dr Califf as Food and Drug Administration (FDA) Commissioner, Who Once Prescribed Marijuana

President Joe Biden announced on Friday that he intends to nominate a new Food and Drug Administration (FDA) commissioner who has acknowledged the potential medical benefits of marijuana and says he actually prescribed a cannabinoid drug as a doctor.

Dr. Robert Califf, who previously served a short stint as the FDA head under the Obama administration, hasn’t been especially vocal about marijuana issues.

But at a 2016 federally hosted research summit on cannabis, he recognized various therapeutic applications for the plant and its components and emphasized that the agency is interested in promoting research and development. “We understand that people have identified a number of possible uses of marijuana and marijuana-derived products. For example, AIDS wasting, epilepsy, neuropathic pain, treatment of spasticity associated with multiple sclerosis, cancer and chemotherapy-induced nausea,” Dr. Califf said.

“And I had the chance to prescribe some of this in my cardiology practice in people with extreme heart failure who get a wasting cachectic syndrome.” Notably, he also said that while FDA had yet to find that botanical marijuana is “safe and effective for any indication,” that’s not to say there aren’t any good uses for it, and additional studies could shed light on the situation.

FDA’s position on cannabis is “not because we’ve had a ton of applications to look at,” he pointed out. “It’s because we haven’t gotten them into the pathway,” Califf said. “What this means is that no one has demonstrated to FDA that any such product is safe or effective for the treatment of any disease or condition. To change that we need studies conducted using marijuana to rigorously assess the safety and effectiveness of marijuana for medical use.”

“Then we need to get those studies submitted to FDA and a marketing application for review under the legal standard set out in the federal Drug and Cosmetic Act,” he said.

“This assures that the drug product meets the statutory standards for approval.” “This is what we really want and we actively encourage it and want to work with people to make this happen,” he added.

“To do this, we know we need to facilitate the work of companies interested in appropriately bringing safe, effective and quality products to market, including scientifically based research concerning these medicinal uses.”

“We believe this process, which includes collaboration with other federal and state agencies, researchers and manufacturers working on issues related to the use of cannabidiol and other constituents of marijuana in the U.S. remains the best way to identify new treatments that are safe and effective for patients and to protect patients from products that are not what they purport to be.”

At the summit, Califf also noted that FDA has approved synthetic cannabis products like Marinol for the treatment of anorexia associated with AIDS and nausea related to chemotherapy treatment.

The approval of these substances “supports the point I made earlier that our decisions on the approval of any medicine relies on the science to determine the safety and effectiveness of new medicines. And it’s also consistent with the approach we’ll continue to take going forward in this area,” he said.

Overall, the remarks suggest that, if confirmed, it doesn’t seem that Califf wouldn’t be hostile toward attempts to explore the therapeutic potential of cannabis. But he does seem to defer to statutory processes within FDA that favor pharmaceutical approaches to these medicines that have so far kept marijuana in a tightly regulated drug category.

Separately, some vaping stakeholders have raised concerns about the prospective nominee, pointing to a 2019 op-ed he authored that advocated for a ban on flavored vape products as a way to mitigate the risks of the e-cigarette or vaping use-associated lung injury (EVALI) crisis.

“I believe that we should move to enact strict regulation to limit the harm done by vaping products, augmented by an aggressive public education program that is particularly aimed at vulnerable young people, but not excluding adults,” Dr. Califf wrote at the time.

However, he acknowledged that an “outright prohibition of vaping products seems impracticable on several grounds,” adding that the “regime of legal prohibition also dissuades people from seeking help with addiction for fear of stigma that might negatively affect future employment and social mobility.”

If Califf does become commissioner, he’ll have his work cut out for him on the cannabis front.

For example, industry stakeholders are eagerly awaiting action by the FDA to allow CBD to be marketed as a food item or dietary supplement.

 The agency has said that it is exploring regulatory pathways to allow for such cannabidiol commerce, but bipartisan lawmakers have introduced legislation this session to force a change.

FDA was mandated under appropriations legislation enacted in 2019 to provide an update on its regulatory approach to CBD, and it did so in March of last year.

The update stated that “FDA is currently evaluating issuance of a risk-based enforcement policy that would provide greater transparency and clarity regarding factors FDA intends to take into account in prioritizing enforcement decisions.”

Another issue that FDA is focusing on concerns delta-8 THC products that are made through a synthetic process using hemp-derived CBD.

The agency issued warnings to consumers about the potential risks of the cannabinoid in September.

FDA also recently announced that it plans to use Reddit and other “novel” data sources to gain a better understanding of public health issues surrounding use of CBD and other “emerging” marijuana derivatives like delta-8 THC.

With respect to broader marijuana policy, FDA would play a critical role in any moves to reschedule or deschedule cannabis.

If a scheduling petition is accepted, the agency would need to assess the scientific, medical and public health implications before submitting that review to the Justice Department with its recommendations.

FDA Acting Commissioner Janet Woodcock, meanwhile, frustrated advocates earlier this year after dodging a congressman’s question about whether marijuana is more harmful than tobacco.  

 

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The Industrial Hemp Industry: An 18.6 Billion Dollar Market by 2027

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The Industrial Hemp Industry: An 18.6 Billion Dollar Market by 2027

 

 

The source cites, the “rise in usage of hemp seed and hemp seed oil in several food applications, increase in awareness regarding advantages of recreational hemp, and surge in demand for hemp-based beauty and personal care products drive the growth of the global industrial hemp market.”

However, complex regulatory structure for the use of industrial hemp hampers the market growth.

Department of Agriculture (USDA)

On the contrary, technological innovations are expected to create lucrative opportunities for market players in the future.”

lucrative opportunities?

Yes… a resounding yes. Industrial hemp has nearly

unlimited potential and the surface of that potential has only been scratched.

Much more remains to be discovered about the possible uses of the robust, multi-purpose substance.

Federal legislation in favor of hemp and many state approvals across the country have been a boon to the industry.

And with immense profits to be made, there is no doubt that companies in the industry, will benefit from it.

The hemp industry has evolved into an environment where the imaginations of creative scientists and inventors,

and business savvy entrepreneurs, will now be fully unleashed, leading to a cascade of innovations and surprising twists and turns.

Advanced technology in hemp will broaden product lines, increase efficiency, and boost production levels, ensuring ample funding for research and development for years to come. Technological innovation in the industrial hemp industry is already making a huge impact on several areas of the industry.

The number of consumer products made from hemp is already mind-boggling.

From personal care items to fuel, the list seems to be endless.

Hemp is here to stay and innovators will discover new ways to exploit the remarkable quality that has been known for years, Technological innovation will be the 

component to gain an edge in a highly competitive marketplace which will undoubtedly take the industry in some exciting and unpredictable directions.

From the grower to the manufacturer, and from the growing facility to the end consumer, technology is transforming the industrial hemp industry in unimaginable, riveting ways for everyone. For those outside the industry, the knotty question is, “How?” Well, according to the latest Allied Market Research Report, it’s the technological advancements in cultivation and machinery that are able to develop hemp plants more efficiently. These continual advancements are astounding, projecting the global industrial hemp market to “reach $18.6 billion by 2027, growing at a CAGR of 22.4% from 2021 to 2027.”

Just What Does $18.6 Billion Market Value Look Like ?

How much is 18.6 billion you ask?  

 

Well, you have come to the right place to learn all about 18.6 billion!
Let’s start with how you would write 18.6 billion with numbers only:
$18,600,000,000
And this is how you would write 18.6 billion with letters only:
Eighteen billion six hundred million
If you take apart 18.6 billion and turn it into millions you get:
18.6 billion = 18,600 million
If you type in 18.6 billion on your calculator, it may come out as a scientific notation of:
1.86E+10 (1.86 x 1010)
OK, enough of the basics. Now we will put 18.6 billion in the context of other things, so you can get a better idea of how much it really is:
Spending: If you had 18.6 billion dollars, you could buy 620,000 cars at $30,000/each or 93,000 houses at $200,000/each.
Travel: If you were to travel 18.6 billion miles, you could fly around the world 746,958 times or take a round trip to the moon 38,928 times.
Savings: If you could save $100,000/year, it would take you 186,000 years to save 18.6 billion dollars. If you could save $10,000 every single day, then it would only take you 5,096 years to save 18.6 billion.
Giving: With 18.6 billion dollars, you could afford to give every man, woman, and child in Canada $516.67.
Living: If you could live for 18.6 billion minutes, you would live until you were 35,388 years old.

Hemp may be the salvation in retooling America for greener, more sustainable domestic manufacturing. Inspirational Technologies is Committed to ” #HempMovesTheChains  #EnvironmentalHemp #ManufacturingHemp #PlanetHemp “

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New `1st Hemp USA News Exclusive ” 11/9/2021

Cannabis stocks rose Monday for the second straight day after a report by Marijuana Moment that Rep. Nancy Mace (R-S.C.)

 

is circulating the States Reform Act as a measure to legalize cannabis on a federal level.

 

Cantor Fitzgerald analyst Pablo Zuanic said late Friday the measure “significantly increases the probability of federal level marijuana reform” during the current term.

 

 

 

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Cannabis Global in Distribution and Purchase Option Agreement for Cannabis Transport System Comply Bag(R)

LOS ANGELES, CA November 10, 2021 Cannabis Global, Inc. , an innovation-oriented company investing in disruptive cannabis technologies, today announces it has entered into a distribution agreement with Humboldt Bliss to distribute the Company’s Comply Bag®, cannabis transport system with integrated smartphone track and trace app.

Cannabis Global

As part of the agreement, the Company also also granted Humboldt Bliss an option to purchase a controlling interest in Ethos Technology LLC, dba Comply Bag®, a wholly-owned subsidiary of Cannabis Global, for $4 million, which controls the products and the associated intellectual property.

David Welch, the managing partner at DRWelch, a Los Angeles-based law firm specializing in regulatory compliance and intellectual property issues with a strong specialization in the cannabis industry, who serves as general counsel of Humboldt Bliss, commented, “We see strong possibilities relative to Comply Bag® especially relating to what most people in the cannabis industry believe will be an upcoming national market for cannabis. Comply Bag® is the best way to stop diversion of cannabis from the legal market into the illicit market and we believe likely to become a standard requirement for Government approved cannabis facilities. As more licensed and legal cannabis commerce occurs, the secure tracking and tracing of cannabis shipments will become a vital interest of both corporations and regulatory agencies.”

 

 Comply Bag® utilizes proven security, tamper resistance, and tracking

features that will allow cannabis companies to transport products

as safely as large financial institutions transport cash and marketable securities.

The product includes the integration of the METRC applications programming interface (API)

into a custom smartphone app that will allow cannabis shippers and receivers to scan shipments

with the information being integrated directly into the leading cannabis track and trace system.

At least 15 states, including California. #CannabisGlobal

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Cannabis Stocks Rise on Federal Marijuana Measure Prospects!

 

Cannabis stocks rose Monday for the second straight day after a report by Marijuana Moment that Rep. Nancy Mace (R-S.C.)

 

is circulating the States Reform Act as a measure to legalize cannabis on a federal level.

2021 Will Be OUR Cannabis Year -Steve Smith

 

Cantor Fitzgerald analyst Pablo Zuanic said late Friday the measure “significantly increases the probability of federal level marijuana reform” during the current term.

 

 

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OG: the Old Gangster is Back

Let’s dig into its weed culture nomenclature — and there are a lot of theories. Some say it’s an acronym for “ocean grown,” “original gangster,” or a shortened version of the word “original.”

If you’ve seen the term “OG” pop up in online media or social feeds, we won’t blame you if you have only a vague idea of what it means.

Most of the time, it seems like an internet slang term that could refer to anything and everything. Urban dictionary’s top definition says it used to mean “original gangster” but is now used as a shorthand for “original.”

A quick Twitter search for #OG ran the gamut from workout goals to happy birthday wishes to pictures of adorable dogs in winter sweaters.

So, what does OG actually mean? The short answer: it means a lot of things to a lot of different people.

In weed culture, OG are two letters you will see in front of a lot of strains that feature the parent strain, OG Kush. Given the frenzied pace of strain breeding right now, hot new strains come and go, but OG Kush has maintained its indisputable popularity. It’s even Weedmaps’ number one most popular strain and reigning Strain Madness champion.

This sativa-leaning hybrid is best known for its epic potency, with THC percentages regularly coming in at 20-25%. Some OG Kush consumers report long-lasting effects that land more in the head than the body, while intensifying sound and color. Described as having an earthy, berry, or citrusy taste, this happy, giggly, and relaxed strain is outstandingly social. No wonder strain breeders seek its parentage.

The OG origin story

Now that we know what to expect from consuming this uber-popular strain, let’s dig into its weed culture nomenclature — and there are a lot of theories. Some say it’s an acronym for “ocean grown,” “original gangster,” or a shortened version of the word “original.”

To know what OG means, you need to know the names of two cannabis growing forefathers who first became friends and roommates in Los Angeles in the early 1990s: Matt “Bubba” Berger, who currently works as a consultant and dispensary owner in Denver’s legal cannabis market, and Josh Del Rosso aka Josh D, Founder and Managing Director of Josh D Farms.

In Berger’s telling, he cultivated the strain in Florida from a random bag of flower he got from a friend in 1992. Another friend, impressed by the strain’s frosty colas, said the buds resembled “kushberries,” which was then shortened to “kush.” In 1996, Berger returned to LA with his kush seeds, and he and Del Rosso planted Kush, Bubba (another of Berger’s strains), and Purple Indica in the crawl space of a rental house they shared.

Word of Del Rosso and Berger’s Kush strain took off and demand soared, reaching $8,000 a pound in the late 90s — that’s around $13,400 in today’s dollars. But with success came imitators hoping to cash in on the Kush phenomena.

Del Rosso and Berger added “OG” to their original Kush to distinguish it from all the others, which stands for “original.” Adding one more layer of confusion, Berger and Del Rosso’s Kush is totally separate and unrelated to landrace kush, an indica that originated in Afghanistan.

OG Kush was hugely popular with 90s consumers, largely for its inclusion in hip hop culture in Los Angeles.

It’s been said it was a favorite of superstar pot celebrity Snoop Dogg and rapper B-Real of the West Coast hip-hop group Cypress Hill (who later released an album titled Greatest Hits from the Bong in 2005).

What does OG mean in pop culture?

So how did the term OG catch on in pop culture? That’s a winding road that leads back to the early 1970s, originating with the LA-based gang the Crips. Originally, it was an all-encompassing term that stood for “original gangster” and simply meant that they were literally the first, e.g. “OG Eastside Crip.”

Over time, the term broadened and evolved, and could refer to someone who showed extreme loyalty to the gang. The term was also used by younger members when referring to the elder gang members as a sign of respect.

As hip-hop and rap music began their mainstream ascent in the 80s, the term OG began to shift from gang culture to rap music and videos when artists sometimes referred to exceptionally badass aspects of gang culture as OG.

See related image detail

Rapper and actor Ice-T may be most responsible for bringing the term to a wider audience with his album and single of the same name,

O.G. Original Gangster,” which reached #7 on 1991’s Billboard rap chart. That could be what inspired Del Rosso and Berger, but that’s impossible to know for sure.

Eventually, the term seeped into establishment culture and continued to expand its meaning. Today you see it everywhere as a reference to something or someone that has exceptionally impressive skills, exemplifies a particular quality, or is the first of its kind.

Image result for ocean grown

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Planting The Seeds of CDB . . .

An entire industry is being built around cannabidiol, or CBD,  

one of the many chemical constituents of the cannabis plant.

 

A message from the Founder of “Inspirational Technologies

      Inspirational Technologies – Steven Smith 2021                            In this Blog,                                             “Planting the Seeds of CBD . . .”,           we wish to Inspire those who are still waiting for the process of “Legitimizing the Claims of CBD” and “MOVE  the CHAINS” forward in the game of CBD. We have had patience, waited on government regulators and Pilot Hemp Programs to give framework to the farmers, cultivators and processing plants. Thank you for your participation, Steven M Smith, Owner/Founder, Inspirational Technologies.

 

Advocates of the compound say it confers all sorts of health benefits,

from mitigating the symptoms of depression and anxiety to treating Glaucoma,

 

 

It’s cropping up in protein powders, bath salts, makeup and even jelly beans.  

 

Medical Advisory Groups for Corporate Subsidiaries are critical for US FDA CBD Compliance

 

But scientists are still unsure of exactly what the benefits — and pitfalls — of CBD are. 

“Society has jumped way ahead of the science on this,” said Margaret Haney,

a professor of neurobiology at Columbia University Medical Center in New York.

Reported benefits have mostly been anecdotal, or they have come from studies involving animal models.

CBD isn’t well understood, nor have there been sufficient studies done in humans, she said.

 

 

Cannabis plants produce a group of chemical compounds called cannabinoids.

The best-known are tetrahydrocannabinol, or THC

(the so-called psychoactive component of the plant that’s associated with the marijuana “high”),

and CBD (a non-intoxicating component of the plant that doesn’t produce a high),

Hemp. Recently, Legal to grow and process for CDB.  

 

Florida Hemp 2019

 

 

Here’s what we do know: CBD can help treat some types of pediatric seizures.

Last year, the FDA approved GW Pharmaceuticals PLC’s Epidiolex for the treatment of seizures associated with two rare forms of epilepsy in patients two years of age and older.

But, to get to that point, GW Pharmaceuticals had to go through a long and rigorous drug-approval process to show the drug’s safety and efficacy through clinical trials.

This hasn’t been done with CBD for any other indication, until now.

While it’s true that CBD has shown promise in pre-clinical and animal trials in addressing a number of issues such as pain, anxiety, neuroinflammation and substance-use disorder,

there’s still not nearly enough peer-reviewed research available, said Ziva Cooper, research director of the Cannabis Research Initiative at the University of California, Los Angeles.

To truly determine the effects of CBD in humans, many further studies need to be done — studies with humans, she said. “Overall, we have very little real data on the therapeutic effects of cannabidiol,” she said.

As for those CBD-based skin products that are popping up on shelves and online, Columbia University’s Haney said she remains skeptical of their marketed benefits.

Many are diluted. It’s a question of both dosage and absorption, she said. “We have no idea how much CBD you would need to rub on your skin for it to have some kind of medical effect,” she said.

 The amount of CBD in a lot of marketed products — even ones that are meant to be taken orally — is so small that we can not make any therapeutic measures for the person using it, said UCLA’s Cooper.

In the few studies that have involved humans, doses were in the hundreds of milligrams, but most CBD-infused products contain much less than that,

which the company says can be used as a daily supplement and help “promote a calm sense of well-being,” it also notes on its website that such statements “have not been evaluated by the Food and Drug Administration.”  

CBD advocates were hoping laws around the compound might loosen up — or at least become clearer — after President Donald Trump signed the 2018 Farm Bill.

Mature Hemp Field Crop
Hemp Is Now A Viable Agriculture Phenomenon

 

The bill legalized hemp, a variety of the cannabis plant that contains no more than 0.3% THC.

December 2018 – The Farm Bill Legalized Hemp

But regulation of CBD, whether derived from hemp or not, is still largely under the FDA’s jurisdiction.

Since CBD is technically an active ingredient in an FDA-approved drug,

companies are not allowed to add it to food or drinks sold across state lines or to sell it as a dietary supplement.

 

Companies are, however, allowed to put the compound into beauty and skin-care products, as cosmetics are not subject to premarket approval by the FDA.

That could explain why drugstore chains like CVS and Walgreens aren’t worried about introducing CBD-infused topical products in their stores.

“People shouldn’t confuse availability with legality,” said former FDA regulatory counsel Jonathan Havens.

The agency has cracked down on unfounded claims, but it has limited resources and can’t get to everyone, so it is focusing mostly on companies making blatant health claims about their products, Havens said.

 

The FDA recently sent warning letters to Advanced Spine and Pain LLC, Nutra Pure LLC and PotNetwork Holdings,

saying the companies violated federal law by advertising their CBD-containing products as potential treatments for ailments including cancer, Alzheimer’s disease, arthritis and more. 

“The FDA wants to protect consumers. The last thing it wants is companies out there marketing CBD products and claiming health benefits without any clinical research to validate that,”

said Rob DiPisa, co-chair of the Cannabis Law Group at law firm Cole Schotz. 

US FDA Fight to Regulate Cannabis (Hemp) More Research is Needed

At the same time, requiring anyone who wants to put a CBD-containing food or beverage on the market to go through the clinical-trial process would “chill the whole CBD market,” he said.

  The FDA is aware of the public’s interest in CBD. Former FDA commissioner Scott Gottlieb put out a statement outlining steps to figure out a framework to lawfully market cannabis

and cannabis-derived products, including  public hearings and formed an internal working group to look into the issue.

DiPisa said he hopes the hearings last  May 2021 will provide more clarity for him and his clients.

“Everyone is running blind right now,” he said.

 

 

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