one of the many chemical constituents of the cannabis plant.
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Advocates of the compound say it confers all sorts of health benefits,
from mitigating the symptoms of depression and anxiety to treating Glaucoma,
It’s cropping up in protein powders, bath salts, makeup and even jelly beans.
Medical Advisory Groups for Corporate Subsidiaries are critical for US FDA CBD Compliance
But scientists are still unsure of exactly what the benefits — and pitfalls — of CBD are.
“Society has jumped way ahead of the science on this,” said Margaret Haney,
a professor of neurobiology at Columbia University Medical Center in New York.
Reported benefits have mostly been anecdotal, or they have come from studies involving animal models.
CBD isn’t well understood, nor have there been sufficient studies done in humans, she said.
Cannabis plants produce a group of chemical compounds called cannabinoids.
The best-known are tetrahydrocannabinol, or THC
(the so-called psychoactive component of the plant that’s associated with the marijuana “high”),
and CBD (a non-intoxicating component of the plant that doesn’t produce a high),
Hemp. Recently, Legal to grow and process for CDB.
Here’s what we do know: CBD can help treat some types of pediatric seizures.
This hasn’t been done with CBD for any other indication, until now.
While it’s true that CBD has shown promise in pre-clinical and animal trials in addressing a number of issues such as pain, anxiety, neuroinflammation and substance-use disorder,
there’s still not nearly enough peer-reviewed research available, said Ziva Cooper, research director of the Cannabis Research Initiative at the University of California, Los Angeles.
To truly determine the effects of CBD in humans, many further studies need to be done — studies with humans, she said. “Overall, we have very little real data on the therapeutic effects of cannabidiol,” she said.
Many are diluted. It’s a question of both dosage and absorption, she said. “We have no idea how much CBD you would need to rub on your skin for it to have some kind of medical effect,” she said.
The amount of CBD in a lot of marketed products — even ones that are meant to be taken orally — is so small that we can not make any therapeutic measures for the person using it, said UCLA’s Cooper.
which the company says can be used as a daily supplement and help “promote a calm sense of well-being,” it also notes on its website that such statements “have not been evaluated by the Food and Drug Administration.”
The bill legalized hemp, a variety of the cannabis plant that contains no more than 0.3% THC.
Since CBD is technically an active ingredient in an FDA-approved drug,
saying the companies violated federal law by advertising their CBD-containing products as potential treatments for ailments including cancer, Alzheimer’s disease, arthritis and more.
“The FDA wants to protect consumers. The last thing it wants is companies out there marketing CBD products and claiming health benefits without any clinical research to validate that,”
said Rob DiPisa, co-chair of the Cannabis Law Group at law firm Cole Schotz.
The FDA is aware of the public’s interest in CBD. Former FDA commissioner Scott Gottlieb put out a statement outlining steps to figure out a framework to lawfully market cannabis
and cannabis-derived products, including public hearings and formed an internal working group to look into the issue.
DiPisa said he hopes the hearings last May 2021 will provide more clarity for him and his clients.
“Everyone is running blind right now,” he said.
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